PI3K: A Protein Involved in Cellular Signaling and Disease (P5954)
PI3K: A Protein Involved in Cellular Signaling and Disease
Phosphatidylinositol 3-kinase (PI3K) is a protein that plays a crucial role in cellular signaling. It is a transmembrane protein that is involved in the phosphatidylinositol (phosphatidylinositol) signaling pathway. This pathway is involved in many cellular processes, including cell growth, differentiation, and survival. PI3K is a protein that is often targeted by drugs because of its role in cellular signaling.
PI3K is a protein that is composed of four transmembrane domains. It has a catalytic active site that is involved in the phosphorylation of the target protein. The catalytic active site is the site where the PI3K protein interacts with other proteins to cause the target protein to phosphorylize. This phosphorylation of the target protein can then trigger a cascade of downstream signaling pathways.
PI3K is a protein that is expressed in many different cell types, including neurons, muscle cells, and blood cells. It is also a protein that is involved in many different cellular processes, including cell growth, differentiation, and survival. For example, PI3K is involved in the regulation of cell growth and in the development of cancer. It is also involved in the regulation of muscle cell size and in the maintenance of muscle mass.
PI3K is a protein that has been targeted by many drugs as a potential drug target. For example, inhibitors of PI3K have been shown to be effective in treating a variety of diseases, including cancer, diabetes, and cardiovascular disease. These inhibitors work by inhibiting the activity of PI3K, which can lead to the inhibition of the signaling pathways that are controlled by PI3K.
In addition to its potential as a drug target, PI3K is also a protein that is often used as a biomarker. For example, the levels of PI3K have been shown to be elevated in certain types of cancer, which can be used as a biomarker for the disease. In addition, the activity of PI3K has been shown to be affected by various factors, including diet, exercise, and environmental factors. This makes PI3K a potential biomarker for the effects of these factors on cellular signaling.
Overall, PI3K is a protein that is involved in many cellular processes and has been shown to be involved in the regulation of many different diseases. As a result, it is a protein that is of interest as a potential drug target and as a biomarker. Further research is needed to fully understand the role of PI3K in cellular signaling and its potential as a drug and biomarker.
Protein Name: Phosphatidylinositol 3-kinase (PI3K) (nonspecified Subtype)
More Common Targets
Phosphatidylinositol 3-kinase complex (PIK3C3, PIK3R4) | Phosphatidylinositol 4-Kinase (PI4K) | Phosphatidylinositol 4-Kinase beta (PI4K-beta) | Phosphatidylinositol 4-phosphate 5-kinase | Phosphatidylinositol N-acetylglucosaminyltransferase | Phosphatidylinositol-5-phosphate 4-kinase | PHOSPHO1 | PHOSPHO2 | PHOSPHO2-KLHL23 | Phosphodiesterase | Phosphodiesterase 1 (PDE1) | Phosphodiesterase 6 (PDE6) | Phosphodiesterase 8 (nons | Phosphodiesterase IV (PDE4) | Phosphoglucomutase 5 pseudogene 1 | Phosphoglycerate kinase | Phospholipase A | Phospholipase A2 | Phospholipase A2, Cytosolic | Phospholipase A2, Secretory (sPLA2) | Phospholipase C | Phospholipase D | Phosphorylase kinase | PHOX2A | PHOX2B | PHPT1 | PHRF1 | PHTF1 | PHTF2 | PHYH | PHYHD1 | PHYHIP | PHYHIPL | PHYKPL | PI15 | PI16 | PI3 | PI4K2A | PI4K2B | PI4KA | PI4KAP1 | PI4KAP2 | PI4KB | PIANP | PIAS1 | PIAS2 | PIAS3 | PIAS4 | PIBF1 | PICALM | PICART1 | PICK1 | PICSAR | PID1 | PIDD1 | PIERCE1 | PIERCE2 | PIEZO1 | PIEZO2 | PIF1 | PIFO | PIGA | PIGB | PIGBOS1 | PIGC | PIGF | PIGG | PIGH | PIGK | PIGL | PIGM | PIGN | PIGO | PIGP | PIGQ | PIGR | PIGS | PIGT | PIGU | PIGV | PIGW | PIGX | PIGY | PIGZ | PIH1D1 | PIH1D2 | PIK3AP1 | PIK3C2A | PIK3C2B | PIK3C2G | PIK3C3 | PIK3CA | PIK3CA-DT | PIK3CB | PIK3CD | PIK3CD-AS1 | PIK3CD-AS2 | PIK3CG | PIK3IP1 | PIK3IP1-DT