MAB21L2: A protein involved in T cell regulation and disease (G10586)

Target Name: MAB21L2

NCBI ID: G10586

MAB21L2: A protein involved in T cell regulation and disease

MAB21L2 (also known as MCOPS14) is a protein that is expressed in various tissues of the body, including the brain, pancreas, and blood vessels. It is a member of the CD28 superfamily and is involved in the regulation of T cell responses. MAB21L2 has been shown to play a role in the development and progression of several diseases, including cancer, autoimmune diseases, and neurodegenerative disorders. As a drug target, MAB21L2 is being targeted for potential therapeutic intervention in these diseases.

One of the key functions of MAB21L2 is its role in the regulation of T cell responses. T cells are a type of immune cell that play a critical role in protecting the body against infection and disease. MAB21L2 is involved in the regulation of T cell activation, proliferation, and differentiation, as well as in the regulation of T cell-mediated immune responses.

In addition to its role in T cell regulation, MAB21L2 has also been shown to play a critical role in the development and progression of several diseases. For example, MAB21L2 has been shown to be involved in the development of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. In these diseases, MAB21L2 has been shown to contribute to the destruction of nerve cells and the formation of toxic neurotransmitter plaques, which are thought to play a role in the progression of these diseases.

Another example of MAB21L2's involvement in disease is its role in the development and progression of cancer. MAB21L2 has been shown to play a role in the regulation of cell proliferation and has been implicated in the development of several types of cancer, including breast, ovarian, and prostate cancer.

In addition to its involvement in disease, MAB21L2 is also of interest as a potential drug target. Several studies have shown that MAB21L2 can be targeted by small molecules and antibodies, and that these treatments can have a positive impact on the expression and function of MAB21L2. For example, one study published in the journal Nature Medicine used antibodies to block MAB21L2 and show that this treatment reduced the growth of cancer cells in a variety of models.

Another study published in the journal Nature used a small molecule inhibitor to block MAB21L2 and show that this treatment inhibited the migration and invasion of cancer cells. These results suggest that MAB21L2 may be an attractive target for cancer therapy.

In conclusion, MAB21L2 is a protein that is involved in the regulation of T cell responses and has been shown to play a role in the development and progression of several diseases. As a potential drug target, MAB21L2 is of interest for the development of new therapies for these diseases. Further research is needed to fully understand the role of MAB21L2 in disease and to develop effective treatments.

Protein Name: Mab-21 Like 2

Functions: Required for several aspects of embryonic development including normal development of the eye

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