Target Name: IL34
NCBI ID: G146433
Other Name(s): IL-34 | MGC34647 | IL34_HUMAN | IL34 variant 1 | Interleukin 34, transcript variant 1 | Interleukin-34 | Interleukin-34 (isoform 1) | interleukin 34 | C16orf77

IL-34: Unlocking Its Potential as A Therapeutic Drug

The IL-34 protein, also known as interleukin-34, is a cytokine that plays a crucial role in the regulation of immune responses and inflammation. It is a member of the interleukin family, which includes proteins that regulate various immune cell functions, such as T cells, B cells, and natural killer cells.

IL-34 is a type of cytokine that is expressed in a variety of tissues throughout the body, including the skin, eyes, and respiratory tract. It is involved in the regulation of immune cell function and has been implicated in a number of diseases, including autoimmune disorders, cancer, and obesity.

One of the key functions of IL-34 is its role in the regulation of immune cell development and function. IL-34 has been shown to promote the growth and survival of immune cells, including T cells and B cells, and has been shown to play a role in the development of cancer.

In addition to its role in immune cell function, IL-34 is also involved in the regulation of inflammation. It has been shown to contribute to the regulation of inflammation and has been implicated in a number of inflammatory diseases, including obesity and autoimmune disorders.

Despite its potential therapeutic applications, IL-34 remains an unexplored drug target. There is currently no cure for many of the diseases that are associated with IL-34, and there is a need for further research to understand its role in these diseases and to develop effective treatments.

In conclusion, IL-34 is a protein that plays a crucial role in the regulation of immune cells and inflammation. While it has the potential to be a drug target, further research is needed to understand its role in various diseases and to develop effective treatments.

Protein Name: Interleukin 34

Functions: Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1

More Common Targets

IL36A | IL36B | IL36G | IL36RN | IL37 | IL3RA | IL4 | IL4I1 | IL4R | IL5 | IL5RA | IL6 | IL6-AS1 | IL6R | IL6R-AS1 | IL6ST | IL6ST-DT | IL6STP1 | IL7 | IL7R | IL9 | IL9R | IL9RP3 | IL9RP4 | ILDR1 | ILDR2 | ILF2 | ILF3 | ILF3-DT | ILK | ILKAP | ILRUN | ILVBL | Imidazoline I2 receptor (I2) | Imidazoline I3 receptor (I3) | Imidazoline receptor | IMMP1L | IMMP2L | IMMT | IMMTP1 | Immunoglobulin A | Immunoglobulin E (IgE) | Immunoglobulin G | Immunoglobulin M | Immunoglobulin-Like Domain Containing Receptor | Immunoproteasome | IMP3 | IMP4 | IMPA1 | IMPA1P1 | IMPA2 | IMPACT | IMPDH1 | IMPDH1P10 | IMPDH1P6 | IMPDH2 | IMPG1 | IMPG2 | INA | INAFM1 | INAFM2 | INAVA | INCA1 | INCENP | INE1 | INE2 | INF2 | ING1 | ING2 | ING2-DT | ING3 | ING4 | ING5 | INGX | INHA | INHBA | INHBA-AS1 | INHBB | INHBC | INHBE | INHCAP | Inhibitor of Apoptosis Proteins (IAPs) | Inhibitory kappaB Kinase (IKK) | INIP | INKA1 | INKA2 | INKA2-AS1 | INMT | INMT-MINDY4 | Innate Repair Receptor (IRR) | INO80 | INO80 complex | INO80B | INO80B-WBP1 | INO80C | INO80D | INO80E | Inositol 1,4,5-Trisphosphate Receptor (InsP3R) | Inositol hexakisphosphate kinase | Inositol Monophosphatase