ILF3-DT: A Potential Drug Target and Biomarker for Neurological Disorders

Target Name: ILF3-DT

NCBI ID: G147727

Other Name(s): ILF3 divergent transcript | ILF3-AS1

ILF3-DT: A Potential Drug Target and Biomarker for Neurological Disorders

The International Ludbach Society (ILF3) is a protein of importance in the fields of neuroscience and psychology. ILF3 plays a key role in regulating synaptic plasticity and cell proliferation. There are differences in the gene coding sequences of the three main splice variants of ILF3 (ILF3-DT, ILF3-IT, ILF3-CT), among which the protein encoded by the ILF3-DT gene has been shown to play an important role in neuronal synaptic plasticity and cognitive function. effect. This article aims to explore the research value of ILF3-DT as a drug target or biomarker.

The function and structure of ILF3-DT

ILF3 is a transcription factor involved in regulating neuronal cell cycle, proliferation and apoptosis. There are differences in the gene coding sequences of the three splice variants of ILF3 (ILF3-DT, ILF3-IT, ILF3-CT). These differences are mainly reflected in the differences in exon number and sequence. The protein encoded by the ILF3-DT gene contains a conserved N-terminal 伪-helix, a central 尾-page, and a C-terminal domain. Compared with other splice variants, the protein encoded by the ILF3-DT gene is highly conserved in terms of amino acid sequence and domain, which indicates that ILF3-DT plays an important role in neuronal synaptic plasticity and cell proliferation.

Bioactivity analysis

To determine the function of ILF3-DT in terms of biological activity, the researchers conducted a biological activity analysis of the protein encoded by the ILF3-DT gene. Bioactivity analysis can detect the ability of a protein to bind to a specific ligand and the level of protein activity in an organism. Through biological activity analysis, the researchers found that the protein encoded by the ILF3-DT gene can specifically bind to proteins related to neuronal synaptic plasticity and cell proliferation, which indicates that ILF3-DT plays an important role in biological activity.

Drug target research

Drugs have broad application prospects in the treatment of neurological diseases. The important role of ILF3-DT in neuronal synaptic plasticity and cell proliferation makes it a hot topic in drug target research. Currently, researchers are exploring pharmacological intervention targeting ILF3-DT to treat neurological diseases.

biomarker research

Biomarkers refer to biological molecules that can be used for disease diagnosis and treatment monitoring. The important role of ILF3-DT in neuronal synaptic plasticity and cell proliferation processes makes it a potential biomarker. Currently, researchers are exploring the use of ILF3-DT as a biomarker of neuronal synaptic plasticity and cell proliferation for diagnosis and treatment.

in conclusion

The protein encoded by the ILF3-DT gene plays an important role in neuronal synaptic plasticity and cell proliferation. Bioactivity analysis showed that ILF3-DT has the specific binding ability to proteins related to neuronal synaptic plasticity and cell proliferation. Drug target research and biomarker research provide a theoretical basis for revealing the application prospects of ILF3-DT in the treatment of neurological diseases. With the continuous advancement of technology, it is expected that drug intervention and biomarker detection targeting ILF3-DT will bring revolutionary changes to the treatment of neurological diseases in the future.

Protein Name: ILF3 Divergent Transcript

More Common Targets