Target Name: HJV
NCBI ID: G148738
Other Name(s): Hemojuvelin | Hemochromatosis type 2 protein | hemojuvelin BMP co-receptor | HFE2A | MGC23953 | hemojuvelin BMP coreceptor | HJV variant a | hemochromatosis type 2 (juvenile) | Hemojuvelin BMP coreceptor | JH | RGM domain family, member C | RGMC_HUMAN | Hemojuvelin (isoform a) | Hemojuvelin BMP co-receptor, transcript variant a | RGMC | HFE2 | repulsive guidance molecule c | haemojuvelin | hemochromatosis type 2 protein | RGM domain family member C

HJV as A Potential Drug Target Or Biomarker for Hemophilia

HJV (Hemojuvelin), a protein expressed in the liver, has been identified as a potential drug target or biomarker for the treatment of various diseases, including hemophilia, sickle cell anemia, and thalassemia. Its role in these conditions, as well as its potential utility as a diagnostic marker, makes HJV an intriguing target for researchers.

Hemophilia is a genetic disorder that affects the body's ability to control blood clotting. People with hemophilia have difficulty forming blood clots, which can lead to excessive bleeding or joint pain. Treatment typically involves the use of clotting factors, which can be expensive and may have

Protein Name: Hemojuvelin BMP Co-receptor

Functions: Acts as a bone morphogenetic protein (BMP) coreceptor (PubMed:18976966). Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis (PubMed:18976966)

More Common Targets

HK1 | HK2 | HK2P1 | HK3 | HKDC1 | HLA Class II Histocompatibility Antigen DM (HLA-DM) | HLA class II histocompatibility Antigen DO (HLA-DO) | HLA class II histocompatibility antigen DP (HLA-DP) | HLA Class II Histocompatibility Antigen DQ8 | HLA class II histocompatibility antigen DR (HLA-DR) | HLA Class II Histocompatibility Antigen, DQ (HLA-DQ) | HLA class II histocompatibility antigen, DRB1-7 beta chain, transcript variant X1 | HLA complex group 16 (non-protein coding), transcript variant X2 | HLA complex group 8 | HLA-A | HLA-B | HLA-C | HLA-DMA | HLA-DMB | HLA-DOA | HLA-DOB | HLA-DPA1 | HLA-DPA2 | HLA-DPA3 | HLA-DPB1 | HLA-DPB2 | HLA-DQA1 | HLA-DQA2 | HLA-DQB1 | HLA-DQB1-AS1 | HLA-DQB2 | HLA-DRA | HLA-DRB1 | HLA-DRB2 | HLA-DRB3 | HLA-DRB4 | HLA-DRB5 | HLA-DRB6 | HLA-DRB7 | HLA-DRB8 | HLA-DRB9 | HLA-E | HLA-F | HLA-F-AS1 | HLA-G | HLA-H | HLA-J | HLA-K | HLA-L | HLA-N | HLA-P | HLA-U | HLA-V | HLA-W | HLCS | HLF | HLTF | HLX | HM13 | HMBOX1 | HMBS | HMCES | HMCN1 | HMCN2 | HMG20A | HMG20B | HMGA1 | HMGA1P2 | HMGA1P4 | HMGA1P7 | HMGA1P8 | HMGA2 | HMGA2-AS1 | HMGB1 | HMGB1P1 | HMGB1P10 | HMGB1P19 | HMGB1P37 | HMGB1P38 | HMGB1P46 | HMGB1P5 | HMGB1P6 | HMGB2 | HMGB2P1 | HMGB3 | HMGB3P1 | HMGB3P14 | HMGB3P15 | HMGB3P19 | HMGB3P2 | HMGB3P22 | HMGB3P24 | HMGB3P27 | HMGB3P30 | HMGB3P6 | HMGB4 | HMGCL | HMGCLL1 | HMGCR | HMGCS1