NUDT10: A Potential Drug Target and Biomarker (G170685)

Target Name: NUDT10

NCBI ID: G170685

NUDT10: A Potential Drug Target and Biomarker

NUDT10 is a novel protein that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and function have made it an attractive target for researchers to investigate, and its potential as a drug may have significant implications for the treatment of these diseases.

The NUDT10 protein is a member of the NUDT family, which is known for its role in the regulation of DNA damage repair and checkpoint pathways. NUDT10 is a 21-kDa protein that is expressed in various tissues and cells, including brain, muscle, and placenta. Its function in these cells is not well understood, but studies have shown that it plays a role in the regulation of cell cycle progression, apoptosis, and inflammation.

One of the key features of NUDT10 is its ability to interact with various DNA-binding proteins, including histone modifications and non-histone modifications. This interaction suggests that NUDT10 may have a role in modifying the expression of genes, and potentially influencing cellular processes such as gene expression, DNA replication, and repair.

In addition to its role in cellular processes, NUDT10 has also been shown to play a role in the regulation of inflammation and immune responses. Studies have shown that NUDT10 is involved in the regulation of the NF-kappa-B signaling pathway, a known regulator of inflammation and immune responses. This suggests that NUDT10 may be a potential target for drugs that are designed to inhibit inflammation and immune responses.

The potential drug targets for NUDT10 are vast, and its functions in various diseases make it an attractive candidate for a variety of treatments. For example, NUDT10 has been shown to be involved in the regulation of cancer cell proliferation, and may be a potential target for drugs that inhibit cell cycle progression. Additionally, its role in the regulation of inflammation and immune responses may make it a potential target for drugs that are designed to inhibit inflammation and boost immune responses.

In conclusion, NUDT10 is a novel protein that has been identified as a potential drug target and biomarker for various diseases. Its unique structure and function have made it an attractive target for researchers to investigate, and its potential as a drug may have significant implications for the treatment of these diseases. Further research is needed to fully understand the role of NUDT10 in various cellular processes and its potential as a drug.

Protein Name: Nudix Hydrolase 10

Functions: Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate

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