Exploring the Potential Applications of STYK1 (NOK) as a Drug Target and Biomarker
Exploring the Potential Applications of STYK1 (NOK) as a Drug Target and Biomarker
STYK1 (Spermidine-Activated ProteinKinase 1) is a protein that plays a crucial role in cellular processes, including DNA replication, repair, and metabolism. As a result, STYK1 has been identified as a potential drug target and biomarker for various diseases. In this article, we will discuss the current understanding of STYK1, its potential applications as a drug target, and its role as a biomarker for various diseases.
Current Understanding of STYK1
STYK1 is a 26 kDa protein that is expressed in various cell types, including eukaryotes, bacteria, and archaea. It is composed of a 166 amino acid protein and a 14 kDa nucleotide-binding domain (NBD). The NBD is responsible for the protein's nuclear localization and functions as a binding site for various nucleotides, including DNA and RNA.
STYK1 has been shown to be involved in various cellular processes, including DNA replication, repair, and metabolism. It has been shown to be involved in the repair of DNA damage,
Protein Name: Serine/threonine/tyrosine Kinase 1
Functions: Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways (By similarity)
More Common Targets
STYX | STYXL1 | STYXL2 | SUB1 | SUB1P1 | Succinate Dehydrogenase Complex | Succinate-CoA ligase (ADP-forming) | SUCLA2 | SUCLG1 | SUCLG2 | SUCLG2-DT | SUCLG2P2 | SUCNR1 | SUCO | SUDS3 | SUFU | SUGCT | SUGP1 | SUGP2 | SUGT1 | SUGT1P1 | SUGT1P2 | SUGT1P3 | SUGT1P4-STRA6LP-CCDC180 | SULF1 | SULF2 | Sulfotransferase | SULT1A1 | SULT1A2 | SULT1A3 | SULT1A4 | SULT1B1 | SULT1C2 | SULT1C3 | SULT1C4 | SULT1C5P | SULT1D1P | SULT1E1 | SULT2A1 | SULT2B1 | SULT4A1 | SULT6B1 | SUMF1 | SUMF2 | SUMO activating enzyme complex | SUMO1 | SUMO1P1 | SUMO1P3 | SUMO2 | SUMO2P21 | SUMO2P3 | SUMO2P6 | SUMO2P8 | SUMO3 | SUMO4 | SUN1 | SUN2 | SUN3 | SUN5 | SUOX | Superoxide dismutase (SOD) | Suppressor of cytokine signaling (SOCS) | SUPT16H | SUPT20H | SUPT20HL1 | SUPT20HL2 | SUPT3H | SUPT4H1 | SUPT5H | SUPT6H | SUPT7L | SUPV3L1 | SURF complex | SURF1 | SURF2 | SURF4 | SURF6 | Survival of motor neuron (SMN) complex | SUSD1 | SUSD2 | SUSD3 | SUSD4 | SUSD5 | SUSD6 | SUV39H1 | SUV39H2 | SUZ12 | SUZ12P1 | SV2A | SV2B | SV2C | SVBP | SVEP1 | SVIL | SVIL-AS1 | SVIL2P | SVIP | SVOP | SVOPL | SWAP complex