PPP1R14BP3: A Potential Drug Target and Biomarker (G100507617)

Target Name: PPP1R14BP3

NCBI ID: G100507617

Other Name(s): protein phosphatase 1 regulatory inhibitor subunit 14B pseudogene 3 | Protein phosphatase 1 regulatory inhibitor subunit 14B pseudogene 3

PPP1R14BP3: A Potential Drug Target and Biomarker

PPP1R14BP3, also known as PPP1R14, is a protein that is expressed in various tissues and cells in the human body. It is a key regulator of the poly (ADP-ribose) polymerase (PARP) pathway, a complex protein that is involved in the regulation of DNA replication and repair. This pathway is critical for the maintenance of cellular health and is often dysregulated in various diseases, including cancer.

The PARP pathway is a highly conserved gene regulatory network that is involved in the regulation of DNA replication and repair. The protein encoded by PPP1R14BP3 is a key regulator of this pathway, and its dysfunction has been implicated in the development and progression of various diseases.

One of the key functions of PPP1R14BP3 is its role in the regulation of DNA replication. This protein plays a critical role in the recruitment of the enzyme PARP, which is responsible for initiating the PARP pathway. PARP is a highly conserved protein that is involved in the regulation of DNA replication and repair. The PPP1R14BP3-PARP interaction is critical for the regulation of DNA replication and has been implicated in the development of various cancers.

In addition to its role in DNA replication, PPP1R14BP3 is also involved in the regulation of DNA repair. This protein plays a critical role in the regulation of the DNA repair pathway, which is involved in the repair of DNA double-strand breaks that can occur during DNA replication. The dysfunction of the DNA repair pathway has been implicated in the development of various diseases, including cancer.

The dysfunction of the PARP pathway has been implicated in the development and progression of various diseases, including cancer. Many studies have suggested that the PPP1R14BP3-PARP interaction is involved in the regulation of cancer cell growth and survival. In addition, this protein has also been implicated in the regulation of cell apoptosis, which is a critical mechanism that helps to remove damaged or dysfunctional cells from the body.

The PPP1R14BP3-PARP interaction is also involved in the regulation of cellular stress responses. This protein plays a critical role in the regulation of cellular stress responses, which are critical for the maintenance of cellular health. The dysfunction of the PARP pathway has been implicated in the development of various diseases, including stress-induced neurodegenerative disorders.

In conclusion, PPP1R14BP3 is a protein that is involved in the regulation of the PARP pathway, which is critical for the maintenance of cellular health. The dysfunction of this pathway has been implicated in the development and progression of various diseases, including cancer. Further research is needed to fully understand the role of PPP1R14BP3 in the regulation of cellular processes and to develop effective therapies that target this protein.

Protein Name: Protein Phosphatase 1 Regulatory Inhibitor Subunit 14B Pseudogene 3

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