CENPBD2P: Potential Drug Target for Cell Death and Cell Proliferation

Target Name: CENPBD2P

NCBI ID: G65996

Other Name(s): MGC111383 | CENPB DNA-binding domains containing 2, pseudogene | CENPBD1P1 | MGC149628 | FLJ18389

CENPBD2P: Potential Drug Target for Cell Death and Cell Proliferation

CENPBD2P, also known as MGC111383, is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the CENPBD family, which includes several similar proteins that are involved in the regulation of cellular processes such as cell division, apoptosis, and inflammation.

One of the unique features of CENPBD2P is its ability to interact with the protein p120GTP, which is a known regulator of apoptosis. This interaction between CENPBD2P and p120GTP suggests that CENPBD2P may play a role in the regulation of cell death, which is a critical aspect of many diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

In addition to its potential role in cell death, CENPBD2P has also been shown to play a role in the regulation of cell proliferation. Several studies have shown that CENPBD2P can inhibit the activity of the protein kinase PDK4, which is involved in cell proliferation. This suggests that CENPBD2P may have potential as a drug target for diseases that are characterized by uncontrolled cell growth, such as cancer.

Another potential function of CENPBD2P is its role in the regulation of inflammation. Several studies have shown that CENPBD2P can modulate the activity of immune cells, including natural killer cells and T cells. This suggests that CENPBD2P may play a role in the regulation of immune responses, which are critical for maintaining the health and function of the immune system.

CENPBD2P is also expressed in the brain, where it is involved in the regulation of neural cell survival and differentiation. This suggests that CENPBD2P may be a potential drug target for neurological diseases, such as Alzheimer's disease and Parkinson's disease.

In conclusion, CENPBD2P is a protein that has been shown to play a role in a variety of cellular processes, including cell death, cell proliferation, and inflammation. Its unique ability to interact with the protein p120GTP also suggests that it may be a potential drug target for a variety of diseases. Further research is needed to fully understand the role of CENPBD2P in these processes and to determine its potential as a drug.

Protein Name: CENPB DNA-binding Domains Containing 2, Pseudogene

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