DOCK5: A Protein Involved in Cancer, Neurodegenerative Diseases

Target Name: DOCK5

NCBI ID: G80005

DOCK5: A Protein Involved in Cancer, Neurodegenerative Diseases

DOCK5 (DKFZp779M164) is a protein that is expressed in various tissues and cell types in the human body. It is a key regulator of cell adhesion and has been implicated in a number of diseases, including cancer.

One of the most significant findings related to DOCK5 is its role in cancer progression. Several studies have shown that high levels of DOCK5 are associated with the development and progression of various types of cancer, including breast, ovarian, and prostate cancers.

In addition to its role in cancer, DOCK5 has also been shown to be involved in a number of other cellular processes that are important for normal cell function. For example, DOCK5 has been shown to play a role in cell signaling, as well as in the regulation of cell division and growth.

DOCK5 has also been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases. Studies have shown that DOCK5 is expressed in the brains of individuals with these conditions and that it is involved in the progression of these diseases.

DOCK5 has also been implicated in a number of other diseases and conditions, including cardiovascular disease, respiratory disease, and autoimmune disorders.

In conclusion, DOCK5 is a protein that has been shown to be involved in a number of important cellular processes in the human body. Its role in cancer progression, neurodegenerative diseases, and other conditions makes it an attractive target for research and development of new treatments. Further research is needed to fully understand the role of DOCK5 in these processes and to develop effective therapies.

Protein Name: Dedicator Of Cytokinesis 5

Functions: Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP (By similarity). Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829)

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