Target Name: CELSR2
NCBI ID: G1952
Other Name(s): Flamingo homolog 3 | CELR2_HUMAN | EGF-like protein 2 | ADGRC2 | CDHF10 | EGF-like-domain, multiple 2 | multiple epidermal growth factor-like domains 3 | epidermal growth factor-like 2 | FLJ42737 | cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) | Epidermal growth factor-like 2 | Flamingo1 | KIAA0279 | FLJ45845 | multiple EGF-like domains protein 3 | FLJ45143 | Multiple EGF-like domains protein 3 | Epidermal growth factor-like protein 2 | Multiple epidermal growth factor-like domains 3 | FLJ34118 | flamingo homolog 3 | Cadherin family member 10 | MEGF3 | cadherin EGF LAG seven-pass G-type receptor 2 | cadherin family member 10 | EGFL2 | epidermal growth factor-like protein 2 | multiple epidermal growth factor-like domains protein 3 | Flamingo 1 | adhesion G protein-coupled receptor C2 | Multiple epidermal growth factor-like domains protein 3 | Cadherin EGF LAG seven-pass G-type receptor 2

CELSR2: A Potential Drug Target and Biomarker

Cysteinyl Esterase L1 (CELSR2) is a protein that is expressed in various tissues throughout the body. It is a member of the superfamily of cysteinyl Esterase (CE) proteins, which are involved in the detoxification of foreign substances in the body. CELSR2 is primarily expressed in the liver and has been shown to play a role in the regulation of cellular processes, including cell growth, apoptosis, and inflammation.

Recent studies have suggested that CELSR2 may have potential as a drug target or biomarker. One of the main reasons for this is the fact that CELSR2 has been shown to be involved in the development and progression of several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. In addition, CELSR2 has been shown to be overexpressed in a variety of cancer types, which suggests that it may be a useful biomarker for these diseases.

Another potential reason for the interest in CELSR2 as a drug target is its role in the regulation of cellular processes that are important for human health. For example, CELSR2 has been shown to play a role in the regulation of cell death, which is important for the maintenance of tissue homeostasis and the development of cancer. In addition, CELSR2 has been shown to be involved in the regulation of cell signaling pathways, which are important for the development and progression of many diseases.

In addition to its potential as a drug target or biomarker, CELSR2 has also been shown to be a promising therapeutic agent in animal models. For example, studies have shown that inhibitors of CELSR2 have been effective in treating a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. In addition, CELSR2 has been shown to be a good candidate for a potential therapeutic agent for the treatment of addiction, as it has been shown to be involved in the regulation of dopamine release in the brain.

Overall, the potential of CELSR2 as a drug target or biomarker is significant, given its involvement in the regulation of cellular processes that are important for human health and its potential therapeutic effects in animal models. Further research is needed to fully understand the potential of CELSR2 as a drug target or biomarker, and to determine the most effective way to use it for the treatment of various diseases.

Protein Name: Cadherin EGF LAG Seven-pass G-type Receptor 2

Functions: Receptor that may have an important role in cell/cell signaling during nervous system formation

More Common Targets

CELSR3 | CEMIP | CEMIP2 | CEMP1 | CENATAC | CEND1 | CENP-A-nucleosome distal (CAD) centromere complex | CENPA | CENPA-CAD (nucleosome distal) complex | CENPA-NAC (nucleosome-associated) complex | CENPB | CENPBD1P | CENPBD2P | CENPC | CENPCP1 | CENPE | CENPF | CENPH | CENPI | CENPIP1 | CENPJ | CENPK | CENPL | CENPM | CENPN | CENPO | CENPP | CENPQ | CENPS | CENPS-CORT | CENPT | CENPU | CENPV | CENPVL1 | CENPW | CENPX | Centralspindlin complex | CEP104 | CEP112 | CEP120 | CEP126 | CEP128 | CEP131 | CEP135 | CEP152 | CEP162 | CEP164 | CEP170 | CEP170B | CEP170P1 | CEP19 | CEP192 | CEP20 | CEP250 | CEP290 | CEP295 | CEP295NL | CEP350 | CEP350-FGFR1OP-MAPRE1 complex | CEP41 | CEP43 | CEP44 | CEP55 | CEP57 | CEP57L1 | CEP63 | CEP68 | CEP70 | CEP72 | CEP72-DT | CEP76 | CEP78 | CEP83 | CEP83-DT | CEP85 | CEP85L | CEP89 | CEP95 | CEP97 | CEPT1 | CER1 | Ceramidase | Ceramide synthase | CERCAM | CERK | CERKL | CERNA2 | CERS1 | CERS2 | CERS3 | CERS3-AS1 | CERS4 | CERS5 | CERS6 | CERS6-AS1 | CERT1 | CES1 | CES1P1 | CES1P2 | CES2