DEFB113: A Potential Drug Target and Biomarker (G245927)

Target Name: DEFB113

NCBI ID: G245927

DEFB113: A Potential Drug Target and Biomarker

DEFB113 (DB113_HUMAN), also known as human exploratory protein (HUSB), is a protein that is expressed in various tissues of the human body. It is a member of the insulin-like growth factor (IGF) family, which is a group of proteins that play a crucial role in cell growth, differentiation and metabolism.

One of the key functions of DEFB113 is its role in cell signaling. It is a potent regulator of cell proliferation and has been shown to play a key role in the development and maintenance of cancer. DEFB113 has been shown to promote the growth and survival of various types of cancer cells, including breast, ovarian, and prostate cancer.

In addition to its role in cancer development, DEFB113 has also been shown to play a key role in the regulation of normal cellular processes. It has been shown to regulate cell adhesion, migration, and invasion, as well as play a role in the development and maintenance of tissues and organs.

DEFB113 is also of interest as a potential drug target. Its unique structure and its role in various cellular processes make it an attractive target for drug development. Several studies have shown that DEFB113 can be effectively targeted with small molecules, including inhibitors of its activity as a potent regulator of cell proliferation.

One of the challenges in the development of DEFB113 as a drug target is its complex structure. DEFB113 has a unique fold, which makes it difficult to predict the exact mechanism of its activity. Additionally, DEFB113 is highly expressed in various tissues, which can make it difficult to selectively target its activity.

Despite these challenges, research into DEFB113 is ongoing. Several studies have shown that DEFB113 can be effectively targeted with small molecules, including inhibitors of its activity as a potent regulator of cell proliferation. These studies have led to the development of several new compounds that have been shown to be effective in inhibiting DEFB113's activity.

In addition to its potential as a drug target, DEFB113 also has potential as a biomarker. Its unique structure and its role in various cellular processes make it an attractive target for the development of biomarkers. Several studies have shown that DEFB113 can be effectively detected in various tissues and fluids, including blood, urine, and tissue samples.

These studies have led to the development of several new biomarkers that have been shown to be effective in detecting DEFB113. These biomarkers can be used to monitor the effectiveness of DEFB113-based therapies and to diagnose and monitor various types of cancer.

In conclusion, DEFB113 is a protein that is of interest as a potential drug target and as a biomarker. Its unique structure and its role in various cellular processes make it an attractive target for the development of new therapies. Further research is needed to fully understand its potential as a drug target and as a biomarker.

Protein Name: Defensin Beta 113

Functions: Has antibacterial activity

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