DENND1C: A Potential Drug Target for Neurological Disorders (G79958)

Target Name: DENND1C

NCBI ID: G79958

DENND1C: A Potential Drug Target for Neurological Disorders

DENND1C (DEN1C-HUMAN) is a protein that is expressed in the brain and is known for its role in the development and progression of various neurological disorders, including Alzheimer's disease. The protein is composed of 120 amino acids and has a calculated molecular weight of 19.9 kDa.

DENND1C is expressed in the brain and is involved in the formation of the endoplasmic reticulum (ER), which is the network of vesicles responsible for the delivery of proteins to different cellular compartments. It is also involved in the regulation of the trafficking of other proteins to the ER, as well as in the degradation of damaged or dysfunctional proteins.

In addition to its role in the ER and protein degradation, DENND1C is also involved in the regulation of cell signaling pathways that are important for the development and progression of neurological disorders. For example, DENND1C has been shown to be involved in the regulation of the formation of neurotransmitter-producing neurons, which are important for the development of disorders such as Alzheimer's disease.

DENND1C is also involved in the regulation of the formation of glial cells, which are support cells for neurons. These cells play a crucial role in maintaining the structure and function of the nervous system and are thought to be involved in the development of various neurological disorders.

DENND1C has also been shown to be involved in the regulation of the development and progression of neurodegenerative diseases, such as Alzheimer's disease. This is thought to be due to its role in the regulation of the formation of neurotransmitter-producing neurons and glial cells, as well as its involvement in the regulation of cell signaling pathways that are important for the development and progression of these diseases.

In conclusion, DENND1C is a protein that is expressed in the brain and is involved in the formation and regulation of the endoplasmic reticulum, as well as the formation of neurotransmitter-producing neurons and glial cells. Its involvement in these processes, as well as its involvement in the regulation of cell signaling pathways that are important for the development and progression of neurological disorders, makes DENND1C an attractive drug target and a potential biomarker for the diagnosis and treatment of these disorders. Further research is needed to fully understand the role of DENND1C in the development and progression of neurological disorders and to determine its potential as a drug.

Protein Name: DENN Domain Containing 1C

Functions: Guanine nucleotide exchange factor (GEF) which may activate RAB8A, RAB13 and RAB35. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form

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