DET1: Gene Linked To Xenobiotic Detoxification (G55070)

Target Name: DET1

NCBI ID: G55070

DET1: Gene Linked To Xenobiotic Detoxification

DET1, also known as DET1 homolog, is a gene that has been identified in various organisms, including humans. It is a member of the detoxification gene family, which includes genes involved in the detoxification of harmful substances in the body. DET1 is a gene that has been shown to be involved in the detoxification of xenobiotics, which are synthetic or foreign substances that can be harmful to the body.

Xenobiotics are often used in agriculture and industrial settings as pesticides, herbicides, or other chemicals. While these substances can be beneficial in certain contexts, they can be harmful to the environment and to human health if not properly managed. The detoxification of xenobiotics is a critical process that helps the body to eliminate these substances from its system.

DET1 is a gene that has been shown to be involved in the detoxification of xenobiotics. It is located on chromosome 19 and has been shown to encode a protein known as DET1. This protein is involved in the detoxification of a wide variety of xenobiotics, including polychlorinated biphenyls (PCBs), triclosan, and other organic compounds.

One of the key functions of DET1 is its ability to transport xenobiotics across the cell membrane. This is accomplished through the use of a protein called DET1 transmembrane protein, which is responsible for driving the transport of DET1 across the membrane. Once inside the cell, DET1 is involved in the detoxification of xenobiotics by participating in various metabolic pathways.

For example, DET1 has been shown to be involved in the metabolism of PCBs, which are a common class of xenobiotics. PCBs can be found in a wide variety of products, including plastics, adhesives, and other industrial chemicals. While these substances can be beneficial in certain contexts, they can be harmful to the environment and to human health if not properly managed. The detoxification of PCBs is an important step in the body's defense against these substances.

DET1 is also involved in the detoxification of other xenobiotics, including triclosan, a commonly used antibiotic. Triclosan is used to treat a wide range of bacterial and viral infections, but it can be harmful if not properly metabolized by the body. DET1 is involved in the metabolism of triclosan by participating in the citric acid cycle, a process that is involved in the production of energy from the metabolism of food.

In addition to its role in the detoxification of xenobiotics, DET1 has also been shown to be involved in the regulation of cellular processes in the body. For example, DET1 has been shown to be involved in the regulation of the cell cycle, a process that is responsible for the growth and division of cells. It is also involved in the regulation of the production of cellular organelles, such as mitochondria and endoplasmic reticulum.

DET1 is a gene that has been shown to be involved in a wide variety of cellular processes in the body. While its specific functions are not yet fully understood, it is clear that DET1 plays an important role in the detoxification of xenobiotics and in the regulation of cellular processes in the body. As research continues to advance, it is likely that new functions for DET1 will be discovered, and it will become an important target for scientists and doctors who are interested in the study of xenobiotics and their effects on human health.

Protein Name: DET1 Partner Of COP1 E3 Ubiquitin Ligase

Functions: Component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation

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