GPR35: A GPCR Receptor for Pain and Neurotransmission (G2859)

Target Name: GPR35

NCBI ID: G2859

GPR35: A GPCR Receptor for Pain and Neurotransmission

G-protein coupled receptor 35 (GPR35) is a protein that plays an important role in cellular signaling. It is a member of the G protein-coupled receptor (GPCR) family, which is a large family of transmembrane proteins that play a key role in cellular signaling. GPR35 is widely expressed in various tissues and is involved in various physiological processes, including sensory perception, neurotransmission, and hormone signaling.

GPR35 is a seven-transmembrane protein that consists of an extracellular domain, a transmembrane domain, and an intracellular domain. The extracellular domain is involved in the formation of the GPCR structure and is responsible for the protein's ability to interact with ligands. The transmembrane domain is responsible for the protein's ability to interact with ligands and for the regulation of intracellular signaling pathways. The intracellular domain is responsible for the protein's ability to interact with other proteins and for the regulation of intracellular signaling pathways.

GPR35 is involved in a wide range of physiological processes, including sensory perception, neurotransmission, and hormone signaling. For example, GPR35 is involved in the regulation of pain perception and neurotransmission. GPR35 has been shown to play a key role in the regulation of pain perception and has been shown to interact with a variety of pain modulators, including opioids and nonsteroidal anti-inflammatory drugs (NSAIDs).

GPR35 has also been shown to play a key role in neurotransmission. GPR35 has been shown to interact with neurotransmitters, including dopamine, serotonin, and GABA. GPR35 has been shown to play a key role in the regulation of neurotransmission and has been shown to interact with a variety of neurotransmitter receptors.

In addition to its involvement in sensory perception and neurotransmission, GPR35 is also involved in the regulation of hormone signaling. GPR35 has been shown to interact with and regulate the activity of various hormone receptors, including insulin, testosterone, and estrogen.

GPR35 is also a potential drug target and may be a useful biomarker for certain diseases. For example, GPR35 has been shown to play a key role in the regulation of pain perception and has been shown to interact with a variety of pain modulators. This makes GPR35 a potential target for pain medications. In addition, GPR35 has been shown to play a key role in the regulation of neurotransmission and has been shown to interact with a variety of neurotransmitter receptors. This makes GPR35 a potential target for neurotransmitter-based therapies.

Overall, GPR35 is a widely expressed and important protein that plays a key role in cellular signaling. Its involvement in various physiological processes makes it a potential drug target and may make it a useful biomarker for certain diseases. Further research is needed to fully understand the role of GPR35 in cellular signaling and to develop effective therapies based on its properties.

Protein Name: G Protein-coupled Receptor 35

Functions: Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins

More Common Targets