KCTD3: A Potential Drug Target for Various Physiological Processes

Target Name: KCTD3

NCBI ID: G51133

KCTD3: A Potential Drug Target for Various Physiological Processes

KCTD3 (MGC43935) is a protein that is expressed in various tissues of the body, including the brain, heart, and lungs. It is a member of the K-type Ca2+ channels, which are a family of transmembrane proteins that play a crucial role in the regulation of ion channels and signaling pathways.

KCTD3 has been identified as a potential drug target due to its involvement in a variety of physiological processes that are important for human health, including brain function, heart health, and cancer progression.

One of the key functions of KCTD3 is its role in the regulation of neuronal excitability. KCTD3 is expressed in neurons and is involved in the formation and maintenance of the resting membrane potential of these cells. This means that it plays a key role in the regulation of the electrical activity of neurons, which is essential for their proper function and communication.

In addition to its role in neuronal excitability, KCTD3 is also involved in the regulation of heart function. The protein is expressed in the heart and is involved in the regulation of the contractility of heart muscle cells. This means that KCTD3 plays a key role in the regulation of heart rate and blood pressure, which are critical for maintaining the proper functioning of the heart.

KCTD3 is also involved in the regulation of cancer progression. The protein is expressed in a variety of cancer types and is involved in the regulation of cell division and the growth of cancer cells. This means that KCTD3 may be a useful target for cancer therapies that aim to inhibit these processes.

Another potential function of KCTD3 is its role in the regulation of inflammation. The protein is expressed in various tissues and is involved in the regulation of inflammation response. This means that KCTD3 may be a useful target for therapies that aim to reduce inflammation and promote healing.

In conclusion, KCTD3 is a protein that is expressed in various tissues of the body and is involved in a variety of physiological processes that are important for human health. As a potential drug target, KCTD3 has the potential to be a valuable tool for the development of new therapies for a variety of diseases.

Protein Name: Potassium Channel Tetramerization Domain Containing 3

Functions: Accessory subunit of potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (HCN3) up-regulating its cell-surface expression and current density without affecting its voltage dependence and kinetics

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