Target Name: ZNF131
NCBI ID: G7690
Other Name(s): zinc finger and BTB domain containing 35 | Zinc finger protein 131 (clone pHZ-10) | zinc finger protein 131 | zinc finger protein 131 (clone pHZ-10) | ZBTB35 | Zinc finger protein 131 | pHZ-10 | ZN131_HUMAN

ZNF131: A Potential Drug Target and Biomarker

Zinc finger and BTB domain containing 35 (ZNF131) is a gene that encodes a protein known for its role in various cellular processes. The ZNF131 gene has been identified as a potential drug target and biomarker due to its unique structure and the involvement of several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Structure and Function

The ZNF131 gene encodes a protein with a molecular weight of approximately 41 kDa. The protein is composed of a N-terminal zinc finger and a BTB domain, which is responsible for protein-protein interactions and is known to play a role in protein stability and localization. ZNF131 is a member of the ZNF gene family, which is known for its involvement in various cellular processes, including cell growth, differentiation, and apoptosis.

Expression and Disease

Several studies have demonstrated that ZNF131 is expressed in various tissues and cells, including human tissues, cancer cells, and neurodegenerative diseases. For example, researchers have found that ZNF131 is expressed in human tissues, including brain, heart, and pancreatic cancer cells. Additionally, the gene has been implicated in several neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

In addition to its expression in neurodegenerative diseases, ZNF131 has also been linked to several other diseases, including cancer. Studies have shown that ZNF131 is expressed in various types of cancer cells, including breast, lung, and ovarian cancer cells. Furthermore, research has suggested that ZNF131 may play a role in cancer progression and the development of resistance to chemotherapy.

Drug Target

The potential drug target for ZNF131 is its unique structure and the involvement of several diseases. The zinc finger and BTB domain of ZNF131 have been shown to play a role in protein-protein interactions and stability, which may make it an attractive target for small molecules. Additionally, the gene has been implicated in several diseases, including cancer and neurodegenerative diseases, which may make it an attractive target for drugs that can treat these conditions.

Biomarker

The potential use of ZNF131 as a biomarker is based on its expression in various tissues and the involvement in several diseases. The protein has been shown to be expressed in various tissues, including cancer cells and neurodegenerative diseases. Furthermore, the gene has been implicated in several diseases, including cancer and neurodegenerative diseases, which may make it an attractive target for biomarkers that can diagnose or monitor the progression of these conditions.

Conclusion

In conclusion, ZNF131 is a gene that has been identified as a potential drug target and biomarker due to its unique structure and the involvement of several diseases. The zinc finger and BTB domain of ZNF131 have been shown to play a role in protein-protein interactions and stability, which may make it an attractive target for small molecules. Furthermore, the gene has been implicated in several diseases, including cancer and neurodegenerative diseases, which may make it an attractive target for biomarkers that can diagnose or monitor the progression of these conditions. Further research is needed to determine the efficacy and safety of ZNF131 as a drug target and biomarker.

Protein Name: Zinc Finger Protein 131

Functions: Plays a role during development and organogenesis as well as in the function of the adult central nervous system (By similarity). May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling

More Common Targets

ZNF132 | ZNF133 | ZNF134 | ZNF135 | ZNF136 | ZNF137P | ZNF138 | ZNF14 | ZNF140 | ZNF141 | ZNF142 | ZNF143 | ZNF146 | ZNF148 | ZNF154 | ZNF155 | ZNF157 | ZNF16 | ZNF160 | ZNF165 | ZNF169 | ZNF17 | ZNF174 | ZNF175 | ZNF177 | ZNF18 | ZNF180 | ZNF181 | ZNF182 | ZNF184 | ZNF185 | ZNF189 | ZNF19 | ZNF195 | ZNF197 | ZNF2 | ZNF20 | ZNF200 | ZNF202 | ZNF204P | ZNF205 | ZNF205-AS1 | ZNF207 | ZNF208 | ZNF209P | ZNF211 | ZNF212 | ZNF213 | ZNF213-AS1 | ZNF214 | ZNF215 | ZNF217 | ZNF219 | ZNF22 | ZNF22-AS1 | ZNF221 | ZNF222 | ZNF223 | ZNF224 | ZNF225 | ZNF225-AS1 | ZNF226 | ZNF227 | ZNF229 | ZNF23 | ZNF230 | ZNF232 | ZNF232-AS1 | ZNF233 | ZNF234 | ZNF235 | ZNF236 | ZNF236-DT | ZNF239 | ZNF24 | ZNF248 | ZNF25 | ZNF250 | ZNF251 | ZNF252P | ZNF252P-AS1 | ZNF253 | ZNF254 | ZNF256 | ZNF257 | ZNF26 | ZNF260 | ZNF263 | ZNF264 | ZNF266 | ZNF267 | ZNF268 | ZNF271P | ZNF273 | ZNF274 | ZNF275 | ZNF276 | ZNF277 | ZNF28 | ZNF280A