Target Name: ZNF112
NCBI ID: G7771
Other Name(s): zinc finger protein 112 | ZNF112 variant 1 | Zinc finger protein 112 (isoform 1) | ZNF228 | zinc finger protein 112 homolog | Zinc finger protein 112, transcript variant 1 | Zfp-112 | ZFP112 | zinc finger protein 112 (Y14) | zinc finger protein 228 | Zinc finger protein 112 | Zinc finger protein 228 | ZN112_HUMAN

ZNF112: A Potential Drug Target and Biomarker

Zinc finger proteins (ZFPs) are a family of transmembrane proteins that play a crucial role in various cellular processes, including gene regulation, DNA replication, and stress responses. ZNF112, a ZNF gene product, has been identified as a potential drug target and biomarker for various diseases.

The ZNF112 gene is located on chromosome 6p21.2 and encodes a protein with 216 amino acid residues. ZNF112 functions as a negative regulator of the transcription factor p21, which is a key regulator of the cell cycle and a target of many anti-cancer drugs.

The ZNF112 protein has unique features that make it an attractive drug target. One of its hallmark features is its ability to interact with various drug targets, including tyrosine kinases, histone deacetylases (HDACs), and transcription factors. This interactivity suggests that ZNF112 could be a useful target for therapeutic interventions aimed at modulating cell behavior, such as cell proliferation, apoptosis, and angiogenesis.

Several studies have investigated the potential role of ZNF112 in various diseases. For example, overexpression of ZNF112 has been shown to promote the growth and survival of cancer cells, suggesting that it may contribute to cancer progression. Additionally, ZNF112 has been shown to play a role in the regulation of cellular stress responses, which could make it a potential target for interventions aimed at treating stress-related diseases.

Another promising aspect of ZNF112 is its potential as a biomarker for various diseases. The ZNF112 protein has been shown to be expressed in a variety of tissues and cells, including cancer cells, fetal tissues, and brain cells. This suggests that it may be a Useful biomarker for tracking disease progression and response to therapeutic interventions.

In conclusion, ZNF112 is a highly promising drug target and biomarker that has the potential to contribute to the development of new therapeutic strategies for various diseases. Further research is needed to fully understand the molecular mechanisms underlying ZNF112's function and to determine its utility as a drug target and biomarker.

Protein Name: Zinc Finger Protein 112

Functions: May be involved in transcriptional regulation

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