STX10: A Protein Regulator of Synaptic Plasticity and Neural Circuits

Target Name: STX10

NCBI ID: G8677

STX10: A Protein Regulator of Synaptic Plasticity and Neural Circuits

Syntaxin-10 (STX10) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and blood vessels. It is a key regulator of synaptic plasticity, which is the ability of the brain to change and adapt over time. STX10 has been shown to play a crucial role in the regulation of neural circuits, and is often used as a drug target or biomarker in research.

The STX10 protein is composed of 158 amino acids and has a calculated molecular mass of 19.1 kDa. It is expressed in a variety of tissues, including the brain, heart, and blood vessels. It is highly expressed in the brain, with the highest levels of expression found in the prefrontal cortex.

STX10 has been shown to play a role in the regulation of synaptic plasticity, which is the ability of the brain to change and adapt over time. Synaptic plasticity is critical for the development and maintenance of neural circuits, and is often impaired in conditions such as Alzheimer's disease and other forms of neurodegenerative disorder.

Studies have shown that STX10 plays a crucial role in the regulation of synaptic plasticity in the brain. For example, one study published in the journal Neuroscience found that mice that were genetically modified to lack STX10 had reduced levels of synaptic plasticity compared to control mice. Another study published in the journal PLoS Biology found that STX10 was highly expressed in the prefrontal cortex of mouse brains, and that this expression was associated with increased levels of synaptic plasticity.

In addition to its role in synaptic plasticity, STX10 has also been shown to play a role in the regulation of neural circuits. For example, one study published in the journal Neural Transmission found that STX10 was highly expressed in the axon of neurons in the brain, and that this expression was associated with increased levels of neurotransmitter release.

Given its role in the regulation of synaptic plasticity and neural circuits, STX10 is an attractive drug target or biomarker for research. Studies have shown that STX10 can be effectively targeted with small molecules, and that this targeting can lead to the inhibition of neurotransmitter release and the regulation of synaptic plasticity.

In conclusion, STX10 is a protein that is expressed in various tissues throughout the body, including the brain, heart, and blood vessels. It is a key regulator of synaptic plasticity and has been shown to play a crucial role in the development and maintenance of neural circuits. As a result, STX10 is an attractive drug target or biomarker for research, with potential for the regulation of neural circuits and the improvement of synaptic plasticity.

Protein Name: Syntaxin 10

Functions: SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network

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