IL27RA: Key Component of IL27 Receptor (G9466)

Target Name: IL27RA

NCBI ID: G9466

IL27RA: Key Component of IL27 Receptor

IL27RA (Interleukin 27 receptor subunit alpha) is a protein that is expressed in various tissues throughout the body, including the immune system, skin, and tissues. It is a member of the IL27 receptor subfamily, which is a group of cytokines and chemokines that play a crucial role in the regulation of immune responses and inflammation.

IL27RA is a cytokine that is produced by various cell types in response to the presence of certain cytokines, such as interleukin-1 (IL-1) and IL-6. It is a key component of the IL27 receptor, which is a protein that is expressed in various tissues throughout the body. The IL27 receptor is a protein that is composed of an extracellular domain, a transmembrane region, and an intracellular domain. The intracellular domain of IL27R contains aYou can see>

Protein Name: Interleukin 27 Receptor Subunit Alpha

Functions: Receptor for IL27. Requires IL6ST/GP130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Acts as a receptor for the neuroprotective peptide humanin as part of a complex with IL6ST/GP130 and CNTFR (PubMed:19386761). Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms

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