Target Name: DEFB104A
NCBI ID: G140596
Other Name(s): Beta-defensin 104 | defensin beta 104A | DEFB4 | Defensin beta 104B | MGC118945 | D104A_HUMAN | hBD-4 | MGC118942 | DEFB-4 | Defensin beta 104A | DEFB104B | Beta-defensin 4 | BD-4 | Defensin, beta 104 | DEFB104 | Defensin, beta 4 | defensin, beta 4 | OTTHUMP00000195799 | MGC118944

DEFB104A: A Potential Drug Target and Biomarker

DEFB104A, also known as Beta-defensin 104, is a protein that is expressed in a variety of human tissues, including the skin, hair, and nails. It is a member of the defensin family, which is a group of proteins that play a critical role in defending against pathogens and other external agents. In this article, we will explore the potential drug targets and biomarkers associated with DEFB104A, as well as its current research and development status.

Potential Drug Targets

DEFB104A is a protein that has been shown to have a variety of potential drug targets. One of the most promising targets is the protein PDGF-BB, which is a key regulator of cell growth and differentiation. studies have shown that DEFB104A can interact with PDGF-BB and can modulate its activity. This suggests that DEFB104A may be a useful drug target for treating conditions that are characterized by uncontrolled cell growth, such as cancer.

Another potential drug target for DEFB104A is the protein TGF-β, which is involved in cell growth and differentiation. studies have shown that DEFB104A can interact with TGF-β and can modulate its activity. This suggests that DEFB104A may be a useful drug target for treating conditions that are characterized by uncontrolled cell growth, such as cancer.

Biomarkers

DEFB104A is also potential biomarker for some diseases, such as cancer, skin infection, and nail fungus. Studies have shown that the expression of DEFB104A is increased in a variety of cancer tissues and that it is involved in the development and progression of cancer. This suggests that DEFB104A may be a useful biomarker for detecting and monitoring the effectiveness of cancer treatments.

Current Research and Development

Current research and development on DEFB104A is focused on the use of it as a drug target and biomarker. Studies have shown that DEFB104A can be effectively targeted with small molecules, such as inhibitors, antibodies, and other therapeutic agents. These studies have also shown that DEFB104A is involved in a variety of cellular processes, including cell signaling, cell adhesion, and cell migration.

In addition to its potential as a drug target and biomarker, DEFB104A is also being studied for its potential use as a diagnostic agent. Studies have shown that DEFB104A can be used as a diagnostic tool for a variety of conditions, including cancer, skin infection, and nail fungus. This suggests that DEFB104A may be a useful diagnostic tool in the future.

Conclusion

In conclusion, DEFB104A is a protein that has the potential to be a drug target and biomarker for a variety of diseases. Its interaction with PDGF-BB and TGF-β suggests that it may be a useful target for treating conditions characterized by uncontrolled cell growth, such as cancer. Its potential as a diagnostic agent also makes it a promising candidate for future studies. Further research is needed to fully understand the potential of DEFB104A and to develop safe and effective drugs and diagnostic agents based on it.

Protein Name: Defensin Beta 104A

Functions: Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103

More Common Targets

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