Target Name: IL17RD
NCBI ID: G54756
Other Name(s): DKFZp434N1928 | IL17RD variant 2 | SEF | sef homolog | IL17RLM | Interleukin-17 receptor D (isoform a) | similar expression to fgf genes | FLJ35755 | OTTHUMP00000213733 | I17RD_HUMAN | IL17Rhom | IL-17 receptor D | Interleukin-17 receptor D | hSef | interleukin 17 receptor D | interleukin-17 receptor-like protein | IL-17RD | HH18 | Interleukin 17 receptor D, transcript variant 2 | MGC133309 | Sef homolog | Interleukin-17 receptor-like protein

IL17RD: The Potential Drug Target for Inflammatory Neurodegenerative Diseases

Inflammatory neurodegenerative diseases, such as multiple sclerosis, rheumatoid arthritis, and progressive neuronale degenerative diseases, are characterized by the persistent and uncontrolled inflammation that leads to progressive damage to the central nervous system (CNS). These conditions have a significant impact on patients' quality of life, and there is currently no effective treatment available to completely alleviate their symptoms. As such, the development of new drug targets and biomarkers for the prevention and treatment of inflammatory neurodegenerative diseases is of great importance. In this article, we will focus on the potential drug target for inflammatory neurodegenerative diseases, IL17RD.

The IL17RD Signaling Pathway

IL17RD is a key regulator of the pro-inflammatory response and has been implicated in the development and progression of inflammatory neurodegenerative diseases. The interleukin-17 (IL17) signaling pathway, which is activated by IL17RD, plays a crucial role in the regulation of inflammation, immune cell function, and neurodegeneration.

IL17RD is a protein that is expressed in various tissues, including immune cells, endothelial cells, and epithelial cells. It is a key regulator of the production and function of IL17, which is a pro-inflammatory cytokine that plays a central role in the regulation of immune and inflammatory responses.

The Breakdown of IL17RD

IL17RD is a protein that is expressed in various tissues throughout the body, including the lungs, liver, heart, kidneys, and central nervous system (CNS). It is involved in the regulation of IL17 production and function, as well as the regulation of immune cell function and neurodegeneration.

Studies have shown that IL17RD is involved in the regulation of various cellular processes, including cell growth, apoptosis, and inflammation. It has been shown to play a role in the regulation of immune cell function, including the regulation of T cell development and function.

The Potential Therapeutic Benefits of IL17RD

The therapeutic benefits of IL17RD are significant, and there is great interest in the use of this protein as a drug target for the prevention and treatment of inflammatory neurodegenerative diseases.

One of the key benefits of IL17RD is its potential as a therapeutic target for multiple sclerosis (MS), rheumatoid arthritis (RA), and progressive neuronale degenerative diseases (PDD). These conditions are characterized by the persistent and uncontrolled inflammation that leads to progressive damage to the central nervous system (CNS).

Studies have shown that inhibition of IL17RD has the potential to alleviate the symptoms of MS, RA, and PDD. In particular, inhibition of IL17RD has been shown to reduce the production of pro-inflammatory cytokines, such as IL-1尾 and IL-6, which are involved in the regulation of inflammation and immune cell function.

Another potential benefit of IL17RD is its potential as a therapeutic target for neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. These conditions are characterized by the progressive loss of brain cells and the progressive damage to the central nervous system (CNS).

IL17RD has been shown to play a role in the regulation of neurodegenerate diseases, including the regulation of neurotransmitter synthesis and release, as well as the regulation of cellular processes that are involved in neurodegeneration.

The Potential biomarker for IL17RD

IL17RD is

Protein Name: Interleukin 17 Receptor D

Functions: Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation (PubMed:12958313, PubMed:12807873). Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK (PubMed:15239952). Mediates JNK activation and may be involved in apoptosis (By similarity). May inhibit FGF-induced FGFR1 tyrosine phosphorylation (By similarity). Might have a role in the early stages of fate specification of GnRH-secreting neurons (By similarity). Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (By similarity)

More Common Targets

IL17RE | IL17REL | IL18 | IL18BP | IL18R1 | IL18RAP | IL19 | IL1A | IL1B | IL1F10 | IL1R1 | IL1R2 | IL1RAP | IL1RAPL1 | IL1RAPL2 | IL1RL1 | IL1RL2 | IL1RN | IL2 | IL20 | IL20RA | IL20RB | IL21 | IL21-AS1 | IL21R | IL21R-AS1 | IL22 | IL22RA1 | IL22RA2 | IL23A | IL23R | IL24 | IL25 | IL26 | IL27 | IL27RA | IL2RA | IL2RB | IL2RG | IL3 | IL31 | IL31RA | IL32 | IL33 | IL34 | IL36A | IL36B | IL36G | IL36RN | IL37 | IL3RA | IL4 | IL4I1 | IL4R | IL5 | IL5RA | IL6 | IL6-AS1 | IL6R | IL6R-AS1 | IL6ST | IL6ST-DT | IL6STP1 | IL7 | IL7R | IL9 | IL9R | IL9RP3 | IL9RP4 | ILDR1 | ILDR2 | ILF2 | ILF3 | ILF3-DT | ILK | ILKAP | ILRUN | ILVBL | Imidazoline I2 receptor (I2) | Imidazoline I3 receptor (I3) | Imidazoline receptor | IMMP1L | IMMP2L | IMMT | IMMTP1 | Immunoglobulin A | Immunoglobulin E (IgE) | Immunoglobulin G | Immunoglobulin M | Immunoglobulin-Like Domain Containing Receptor | Immunoproteasome | IMP3 | IMP4 | IMPA1 | IMPA1P1 | IMPA2 | IMPACT | IMPDH1 | IMPDH1P10 | IMPDH1P6