Target Name: STRIT1
NCBI ID: G100507537
Other Name(s): Dwarf open reading frame | Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF | DWORF_HUMAN | DWORF | Small transmembrane regulator of ion transport 1 | SERCA regulator DWORF | small transmembrane regulator of ion transport 1

STRIT1: A Potential Drug Target and Biomarker

STRIT1, also known as STAR-1 (stimulated by activator of the nuclear enzyme RAD-A1), is a gene that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. Its unique function and expression have made it an attractive target for researchers to investigate, and potentially for drug developers to exploit.

STRIT1 is a non-coding RNA molecule that has been shown to play a critical role in the regulation of gene expression and has been identified as a potential drug target in various diseases. It is a key regulator of the cell's response to environmental stimuli and has been shown to play a role in the regulation of cell cycle progression, apoptosis, and inflammation.

One of the key functions of STRIT1 is its ability to induce apoptosis in response to various stimuli, including chemotherapy drugs, toxins, and radiation. This process is thought to be a key mechanism by which STRIT1 contributes to the regulation of cell death and has implications for the development of cancer.

STRIT1 has also been shown to play a role in the regulation of cell cycle progression and the maintenance of stem cell properties. It has been shown to promote the growth and survival of stem cells, and to inhibit the differentiation of stem cells into adult tissues. This suggests that STRIT1 may have implications for the development of neurodegenerative disorders.

In addition to its role in cell cycle regulation, STRIT1 has also been shown to play a role in the regulation of inflammation. It has been shown to contribute to the regulation of immune cell function and to play a role in the regulation of inflammation. This suggests that STRIT1 may have implications for the development of autoimmune diseases.

STRIT1 has also been shown to play a role in the regulation of cellular signaling pathways, including the PI3K/Akt signaling pathway. This pathway is involved in the regulation of various cellular processes, including cell survival, growth, and inflammation, and is a key target for many diseases, including cancer.

Given its unique function and its role in the regulation of various cellular processes, it is not surprising that STRIT1 has generated a lot of interest among researchers and drug developers. Many studies have investigated its potential as a drug target and have shown that it has a wide range of potential therapeutic applications.

One of the most promising aspects of STRIT1 is its ability to induce apoptosis in response to various stimuli, including chemotherapy drugs, toxins, and radiation. This process is thought to be a key mechanism by which STRIT1 contributes to the regulation of cell death and has implications for the development of cancer. Additionally, its role in cell cycle regulation and its contribution to the regulation of inflammation make it a promising target for the development of neurodegenerative disorders and autoimmune diseases.

STRIT1 has also been shown to play a role in the regulation of cellular signaling pathways, including the PI3K/Akt signaling pathway. This pathway is involved in the regulation of various cellular processes, including cell survival, growth, and inflammation, and is a key target for many diseases, including cancer.

STRIT1 has also been shown to contribute to the regulation of stem cell properties. It has been shown to promote the growth and survival of stem cells, and to inhibit the differentiation of stem cells into adult tissues. This suggests that STRIT1 may have implications for the development of neurodegenerative disorders.

In conclusion, STRIT1 is a gene that has been identified as a potential drug target and biomarker for various diseases. Its unique function and expression have made it an attractive target for researchers to investigate, and potentially for drug developers to exploit. Further studies are needed to fully understand its potential role in the regulation of cellular processes and to determine its potential therapeutic applications.

Protein Name: Small Transmembrane Regulator Of Ion Transport 1

Functions: Enhances the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by displacing ATP2A1/SERCA1 inhibitors, thereby acting as a key regulator of skeletal muscle activity. Does not directly stimulate SERCA pump activity. Enhances sarcoplasmic reticulum Ca(2+) uptake and myocyte contractility by displacing the SERCA inhibitory peptides sarcolipin (SLN), phospholamban (PLN) and myoregulin (MRLN)

More Common Targets

STRN | STRN3 | STRN4 | STS | STT3A | STT3A-AS1 | STT3B | STUB1 | STUM | STX10 | STX11 | STX12 | STX16 | STX16-NPEPL1 | STX17 | STX17-DT | STX18 | STX18-AS1 | STX18-IT1 | STX19 | STX1A | STX1B | STX2 | STX3 | STX4 | STX5 | STX5-DT | STX6 | STX7 | STX8 | STXBP1 | STXBP2 | STXBP3 | STXBP4 | STXBP5 | STXBP5-AS1 | STXBP5L | STXBP6 | STYK1 | STYX | STYXL1 | STYXL2 | SUB1 | SUB1P1 | Succinate Dehydrogenase Complex | Succinate-CoA ligase (ADP-forming) | SUCLA2 | SUCLG1 | SUCLG2 | SUCLG2-DT | SUCLG2P2 | SUCNR1 | SUCO | SUDS3 | SUFU | SUGCT | SUGP1 | SUGP2 | SUGT1 | SUGT1P1 | SUGT1P2 | SUGT1P3 | SUGT1P4-STRA6LP-CCDC180 | SULF1 | SULF2 | Sulfotransferase | SULT1A1 | SULT1A2 | SULT1A3 | SULT1A4 | SULT1B1 | SULT1C2 | SULT1C3 | SULT1C4 | SULT1C5P | SULT1D1P | SULT1E1 | SULT2A1 | SULT2B1 | SULT4A1 | SULT6B1 | SUMF1 | SUMF2 | SUMO activating enzyme complex | SUMO1 | SUMO1P1 | SUMO1P3 | SUMO2 | SUMO2P21 | SUMO2P3 | SUMO2P6 | SUMO2P8 | SUMO3 | SUMO4 | SUN1 | SUN2 | SUN3 | SUN5 | SUOX | Superoxide dismutase (SOD)