Research on KCTD14: Potential Drug Target Or Biomarker (G65987)

Target Name: KCTD14

NCBI ID: G65987

Other Name(s): KCD14_HUMAN | BTB/POZ domain-containing protein KCTD14 (isoform 1) | KCTD14 variant 1 | potassium channel tetramerization domain containing 14 | Potassium channel tetramerization domain containing 14, transcript variant 1 | potassium channel tetramerisation domain containing 14 | BTB/POZ domain-containing protein KCTD14

Research on KCTD14: Potential Drug Target Or Biomarker

KCTD14 (KCD14_HUMAN), a protein encoded in the human gene KCTD14, is a protein that is involved in various cellular processes in the human body. It is a scaffold protein that plays a crucial role in the assembly and disassembly of microtubules in the cytosol. KCTD14 is a protein that has been identified as a potential drug target or biomarker in various diseases, including cancer. In this article, we will discuss the research on KCTD14 and its potential as a drug target or biomarker.

KCTD14 is a protein that is composed of 254 amino acid residues. It has a molecular weight of 31 kDa and a pre-pfolded structure of 15.8 nm. KCTD14 is a scaffold protein that can interact with a variety of protein partners, including microtubules and other cytoskeleton components. It plays a critical role in the assembly and disassembly of microtubules in the cytosol.

KCTD14 is a protein that has been identified as a potential drug target or biomarker in various diseases, including cancer. For example, studies have shown that KCTD14 is overexpressed in various types of cancer, including breast, ovarian, and colorectal cancers. Overexpression of KCTD14 has been shown to promote the growth and survival of cancer cells, suggesting that it may be a useful target for cancer treatments.

In addition to its potential as a drug target, KCTD14 has also been identified as a biomarker for various diseases. For example, studies have shown that KCTD14 is increased in the blood of patients with cardiovascular disease, including heart failure and coronary artery disease. Additionally, KCTD14 has been shown to be increased in the urine of patients with urinary tract cancer. These findings suggest that KCTD14 may be a useful biomarker for various diseases.

KCTD14 has also been shown to play a critical role in the regulation of cellular processes in the human body. For example, studies have shown that KCTD14 is involved in the regulation of cell division, cell migration, and the assembly of microtubules in the cytosol. Additionally, KCTD14 has been shown to play a role in the regulation of ion channels in the membrane of cells, which can affect the flow of electrical current through the cell.

In conclusion, KCTD14 is a protein that has been identified as a potential drug target or biomarker in various diseases. Its role in the regulation of cellular processes in the human body makes it an attractive target for researchers to investigate further. Further studies are needed to determine the full potential of KCTD14 as a drug or biomarker.

Protein Name: Potassium Channel Tetramerization Domain Containing 14

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