Target Name: GPR176
NCBI ID: G11245
Other Name(s): Gm1012 | G-protein coupled receptor 176 | GP176_HUMAN | HB-954 | GPR176 variant 1 | GPR | G-protein coupled receptor 176 (isoform 1) | Probable G-protein coupled receptor 176 | G protein-coupled receptor 176, transcript variant 1 | probable G-protein coupled receptor 176 | G protein-coupled receptor 176 | Putative G protein coupled receptor

GPR176: A Potential Drug Target for Pain Disorders

GPR176 (also known as Gm1012) is a protein that is expressed in the brain and is known for its role in the regulation of pain signaling. It is a G protein-coupled receptor (GPCR), which means that it is a receptor that is targeted by a protein called G protein. The GPCR system is a complex cell signaling system that is involved in a wide range of physiological processes, including pain signaling.

GPR176 is a transmembrane protein that is located in the endoplasmic reticulum (ER) and is involved in the regulation of pain signaling. It is a potent modulator of pain signaling, with studies showing that it can inhibit the activity of pain-related GPCRs and modulate the activity of non-pain-related GPCRs. This suggests that GPR176 may be a useful drug target for the treatment of pain disorders.

GPR176 is also known as Gm1012 because it is a member of the Gm1012 family of GPCRs. The Gm1012 family is a subset of the GPCR family that includes GPR82, GPR83, GPR85, GPR86, and GPR87. These proteins are involved in a wide range of physiological processes, including pain signaling, neurodegenerative diseases, and sensory processing.

GPR176 is expressed in the brain and is involved in the regulation of pain signaling in this Organ. It is a potent modulator of pain signaling, with studies showing that it can inhibit the activity of pain-related GPCRs and modulate the activity of non-pain-related GPCRs. This suggests that GPR176 may be a useful drug target for the treatment of pain disorders.

GPR176 is a transmembrane protein that is located in the endoplasmic reticulum (ER) and is involved in the regulation of pain signaling. It is a potent modulator of pain signaling, with studies showing that it can inhibit the activity of pain-related GPCRs and modulate the activity of non-pain-related GPCRs. This suggests that GPR176 may be a useful drug target for the treatment of pain disorders.

Protein Name: G Protein-coupled Receptor 176

Functions: Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production

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