Target Name: KCTD12
NCBI ID: G115207
Other Name(s): predominantly fetal expressed T1 domain | FLJ33073 | potassium channel tetramerisation domain containing 12 | Predominantly fetal expressed T1 domain | PFET1 | Predominantly fetal expressed T1 domain (PFET1) | testicular tissue protein Li 100 | BTB/POZ domain-containing protein KCTD12 | C13orf2 | PFETIN | Pfetin | Potassium channel tetramerisation domain containing 12 | KIAA1778 | potassium channel tetramerization domain containing 12 | KCD12_HUMAN | Potassium channel tetramerization domain containing 12

KCTD12: A Potential Drug Target for Placenta and Nervous System

The KCTD12 protein is a protein that is primarily expressed in the placental tissue, specifically in the placenta. It is a member of the T1 domain family, which is a common protein domain found in many proteins that play important roles in cell signaling and communication.

The KCTD12 protein is known for its role in the regulation of cell proliferation and survival. It has been shown to play a role in the development and maintenance of the placenta, and has been linked to the formation of blood vessels in the placenta.

Research has also suggested that KCTD12 may be a potential drug target or biomarker for certain diseases. For example, some studies have suggested that inhibiting the activity of KCTD12 may be effective in treating certain forms of cancer, such as melanoma and breast cancer.

Additionally, KCTD12 has also been shown to be involved in the regulation of cellular processes that are important for the development and maintenance of the nervous system. This suggests that it may be a potential drug target or biomarker for conditions related to the nervous system, such as Alzheimer's disease.

Overall, the KCTD12 protein is a promising candidate for further research and potential drug development. While more research is needed to fully understand its functions and potential uses, its presence in the placenta and its potential links to drug targets and biomarkers make it a valuable tool for scientists and doctors alike.

Protein Name: Potassium Channel Tetramerization Domain Containing 12

Functions: Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity)

More Common Targets

KCTD13 | KCTD13-DT | KCTD14 | KCTD15 | KCTD16 | KCTD17 | KCTD18 | KCTD19 | KCTD2 | KCTD20 | KCTD21 | KCTD21-AS1 | KCTD3 | KCTD4 | KCTD5 | KCTD5P1 | KCTD6 | KCTD7 | KCTD8 | KCTD9 | KDELR1 | KDELR2 | KDELR3 | KDF1 | KDM1A | KDM1B | KDM2A | KDM2B | KDM3A | KDM3B | KDM4A | KDM4B | KDM4C | KDM4D | KDM4E | KDM5A | KDM5A-GATAD1-EMSY chromatin complex | KDM5B | KDM5C | KDM5D | KDM6A | KDM6B | KDM7A | KDM7A-DT | KDM8 | KDR | KDSR | KEAP1 | Kelch-like protein | KERA | Keratin | KHDC1 | KHDC1L | KHDC1P1 | KHDC3L | KHDC4 | KHDRBS1 | KHDRBS2 | KHDRBS3 | KHK | KHNYN | KHSRP | KHSRPP1 | KIAA0040 | KIAA0087 | KIAA0232 | KIAA0319 | KIAA0319L | KIAA0408 | KIAA0513 | KIAA0586 | KIAA0753 | KIAA0754 | KIAA0825 | KIAA0930 | KIAA1107 | KIAA1143 | KIAA1191 | KIAA1210 | KIAA1217 | KIAA1328 | KIAA1522 | KIAA1549 | KIAA1549L | KIAA1586 | KIAA1614 | KIAA1656 | KIAA1671 | KIAA1671-AS1 | KIAA1755 | KIAA1958 | KIAA2012 | KIAA2013 | KIAA2026 | KICS2 | KIDINS220 | KIF11 | KIF12 | KIF13A | KIF13B