Target Name: ZKSCAN5
NCBI ID: G23660
Other Name(s): zfp-95 | Zfp-95 | KIAA1015 | ZFP95 | Zinc finger protein 95 homolog | zinc finger protein 95 homolog | ZKSCAN5 variant 1 | zinc finger protein homologous to Zfp95 in mouse | Zinc finger protein with KRAB and SCAN domains 5 (isoform a) | Zinc finger with KRAB and SCAN domains 5 | zinc finger protein with KRAB and SCAN domains 5 | ZFP-95 | Zinc finger protein with KRAB and SCAN domains 5 | ZNF914 | zinc finger with KRAB and SCAN domains 5 | Zinc finger with KRAB and SCAN domains 5, transcript variant 1 | ZKSC5_HUMAN | ZSCAN37 | ZKSCAN5 variant 2 | Zinc finger with KRAB and SCAN domains 5, transcript variant 2 | Zinc finger protein homologous to Zfp95 in mouse

ZKSCAN5: A Promising Drug Target and Biomarker

ZKSCAN5, also known as zfp-95, is a gene that encodes a protein involved in the intracellular signaling pathway known as the TORC1 complex. The TORC1 complex is a group of transcription factors that regulates various cellular processes, including cell growth, metabolism, and stress responses. ZKSCAN5 has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases.

The TORC1 complex is composed of several subunits, including TOR1 (TORC1), TOR2, TOR3, and TOR4. These subunits form a complex structure that interacts with various target genes to regulate their expression levels. ZKSCAN5 is a key member of the TORC1 complex, and its function in the pathway has been extensively studied.

Studies have shown that ZKSCAN5 plays a critical role in the regulation of cellular processes, including cell growth, apoptosis, and autophagy. It has been shown to regulate the levels of various cellular signaling pathways, including the TOR signaling pathway.

In addition to its role in the TORC1 complex, ZKSCAN5 has also been shown to play a role in the regulation of cellular stress responses. It has been shown to modulate the levels of stress-responsive genes, including those involved in DNA damage repair and cell cycle regulation.

Given its involvement in multiple cellular processes, ZKSCAN5 has potential as a drug target for a variety of diseases. Studies have shown that inhibiting the activity of ZKSCAN5 has the potential to treat various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases.

In cancer, ZKSCAN5 has been shown to have a negative impact on cell proliferation and survival. For example, studies have shown that inhibiting the activity of ZKSCAN5 has the potential to enhance the effectiveness of various anti-cancer drugs, including chemotherapy and targeted therapies.

In neurodegenerative disorders, ZKSCAN5 has been shown to play a role in the regulation of cellular processes that are involved in the development and progression of these disorders. For example, studies have shown that ZKSCAN5 is involved in the regulation of neurotransmitter synthesis and release, as well as the modulation of cellular stress responses.

In autoimmune diseases, ZKSCAN5 has been shown to play a role in the regulation of immune cell function and the development of autoimmune diseases. For example, studies have shown that ZKSCAN5 is involved in the regulation of the production and function of T cells, which are a key component of the immune system.

In conclusion, ZKSCAN5 is a promising drug target and biomarker for a variety of diseases. Its involvement in the TORC1 complex and its potential functions as a negative regulator of cellular stress responses make it an attractive target for drug development. Further research is needed to fully understand the role of ZKSCAN5 in cellular processes and its potential as a drug.

Protein Name: Zinc Finger With KRAB And SCAN Domains 5

Functions: May be involved in transcriptional regulation

More Common Targets

ZKSCAN7 | ZKSCAN8 | ZKSCAN8P1 | ZMAT1 | ZMAT2 | ZMAT3 | ZMAT4 | ZMAT5 | ZMIZ1 | ZMIZ1-AS1 | ZMIZ2 | ZMPSTE24 | ZMYM1 | ZMYM2 | ZMYM3 | ZMYM4 | ZMYM4-AS1 | ZMYM5 | ZMYM6 | ZMYND10 | ZMYND11 | ZMYND12 | ZMYND15 | ZMYND19 | ZMYND8 | ZNF10 | ZNF100 | ZNF101 | ZNF106 | ZNF107 | ZNF112 | ZNF114 | ZNF117 | ZNF12 | ZNF121 | ZNF124 | ZNF131 | ZNF132 | ZNF133 | ZNF134 | ZNF135 | ZNF136 | ZNF137P | ZNF138 | ZNF14 | ZNF140 | ZNF141 | ZNF142 | ZNF143 | ZNF146 | ZNF148 | ZNF154 | ZNF155 | ZNF157 | ZNF16 | ZNF160 | ZNF165 | ZNF169 | ZNF17 | ZNF174 | ZNF175 | ZNF177 | ZNF18 | ZNF180 | ZNF181 | ZNF182 | ZNF184 | ZNF185 | ZNF189 | ZNF19 | ZNF195 | ZNF197 | ZNF2 | ZNF20 | ZNF200 | ZNF202 | ZNF204P | ZNF205 | ZNF205-AS1 | ZNF207 | ZNF208 | ZNF209P | ZNF211 | ZNF212 | ZNF213 | ZNF213-AS1 | ZNF214 | ZNF215 | ZNF217 | ZNF219 | ZNF22 | ZNF22-AS1 | ZNF221 | ZNF222 | ZNF223 | ZNF224 | ZNF225 | ZNF225-AS1 | ZNF226 | ZNF227