PPP1R12C: A Drug Target / Disease Biomarker (G54776)

Target Name: PPP1R12C

NCBI ID: G54776

PPP1R12C: A Drug Target / Disease Biomarker

PPP1R12C is a gene that has been identified as a potential drug target or biomarker for the treatment of various diseases, including cancer. The gene is located on chromosome 12 and has been shown to play a role in the development and progression of several diseases, including cancer.

Recent studies have shown that PPP1R12C is involved in the regulation of cell growth, apoptosis (programmed cell death), and angiogenesis (the formation of new blood vessels). These processes are important for the development and progression of cancer, as well as other diseases.

One of the key ways that PPP1R12C is involved in cancer is its role in the regulation of the blood-brain barrier (BBB). The BBB is a barrier that separates the brain from the surrounding blood vessels, and it helps to protect the brain from the harmful effects of drugs and other substances. However, cancer cells can often bypass the BBB and invade the brain, leading to the development of brain metastases.

Research has shown that PPP1R12C plays a role in the regulation of the BBB by controlling the activity of a protein called FAK. FAK is a cytoskeleton protein that is involved in many different processes in the body, including cell adhesion, migration, and invasion.

In addition to its role in the BBB, PPP1R12C has also been shown to be involved in the regulation of cell apoptosis. Apoptosis is a natural process that helps the body to remove damaged or dysfunctional cells, such as cancer cells. However, cancer cells can often evade the normal apoptosis pathway, leading to the development of cancer.

Research has shown that PPP1R12C plays a role in the regulation of apoptosis by controlling the activity of a protein called BCL-2. BCL-2 is a transcription factor that is involved in the regulation of many different genes, including those that are involved in cell apoptosis.

PPP1R12C is also involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed in the body. Angiogenesis is important for the development and maintenance of normal tissues and organs, but it is also involved in the development of many diseases, including cancer.

Research has shown that PPP1R12C plays a role in the regulation of angiogenesis by controlling the activity of a protein called TGF-β. TGF-β is a transcription factor that is involved in the regulation of many different genes, including those that are involved in cell growth, angiogenesis, and cancer.

In conclusion, PPP1R12C is a gene that has been shown to play a role in the development and progression of many diseases, including cancer. Its involvement in the regulation of cell growth, apoptosis, and angiogenesis makes it an attractive target for drug development. Further research is needed to fully understand the role of PPP1R12C in these processes and to develop effective treatments for the treatment of these diseases.

Protein Name: Protein Phosphatase 1 Regulatory Subunit 12C

Functions: Regulates myosin phosphatase activity

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