Understanding ZBTB18: A Potential Drug Target (G10472)

Target Name: ZBTB18

NCBI ID: G10472

Understanding ZBTB18: A Potential Drug Target

ZBTB18 (Zinc Finger Protein C2H2-171) is a protein that is expressed in various tissues of the human body, including the brain, heart, and kidneys. It is a member of the zinc finger gene family, which is a family of proteins that contain a zinc finger domain. The zinc finger domain is a unique structural feature that consists of a helix and a zinc atom, which is usually found in the middle of the protein sequence.

One of the unique aspects of ZBTB18 is its structure. It has a unique molecular shape, which is composed of a long alpha-helices that are connected to the zinc atom. The alpha-helices are composed of a series of amino acids that are arranged in a specific order, which is important for the protein's function. The zinc atom is located at the end of the alpha-helices, and it is surrounded by several amino acids.

The function of ZBTB18 is not well understood, but it is believed to play a role in various physiological processes in the body. It is involved in the regulation of cellular processes, including cell growth, apoptosis, and inflammation. It is also thought to be involved in the development and progression of certain diseases, such as cancer.

Due to its unique structure and its involvement in various physiological processes, ZBTB18 has been identified as a potential drug target. Researchers are studying the zinc finger domain and its potential functions to develop new treatments for various diseases.

One of the main advantages of targeting ZBTB18 is its small size and its ability to be easily modified. This allows researchers to study the protein's interactions with other molecules and to develop new treatments that specifically target the zinc finger domain.

Another advantage of ZBTB18 is its expression in various tissues, which makes it an attractive target for researchers who are studying the protein's functions in different organs and tissues. This allows researchers to study the protein's effects on the structure and function of different tissues and to develop new treatments that are specific to these tissues.

In conclusion, ZBTB18 is a protein that is expressed in various tissues of the human body and is thought to play a role in various physiological processes. Its unique structure and its involvement in various diseases make it an attractive target for researchers who are studying the protein's functions and developing new treatments. Further research is needed to fully understand the protein's role in the body and to develop effective treatments for various diseases.

Protein Name: Zinc Finger And BTB Domain Containing 18

Functions: Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus

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