Target Name: ZDHHC11
NCBI ID: G79844
Other Name(s): ZDH11_HUMAN | zinc finger, DHHC domain containing 11 | ZNF399 | ZDHHC11 variant 2 | Zinc finger protein 399 | probable palmitoyltransferase ZDHHC11 | Palmitoyltransferase ZDHHC11 | Zinc finger, DHHC domain containing 11 | DHHC-11 | Zinc finger DHHC domain containing 11 (ZDHHC11) | zinc finger DHHC domain-containing protein 11 | Zinc finger DHHC domain-containing protein 11 | Palmitoyltransferase ZDHHC11 (isoform 2) | FLJ13153 | zinc finger DHHC-type containing 11 | zinc finger protein 399 | Zinc finger DHHC-type containing 11, transcript variant 2

ZDHHC11: A Potential Drug Target and Biomarker

ZDHHC11, also known as ZDH11_HUMAN, is a protein that is expressed in various tissues of the human body. It is a member of the Zinc Finger N-Terminal domain (ZFNTD) family, which is a family of proteins that contain a zinc finger and a N-terminal domain. ZDHHC11 is characterized by its N-terminal domain, which is composed of a unique set of amino acids that is highly conserved across various species.

The ZDHHC11 protein is of interest as a potential drug target or biomarker due to its unique structure and the functions it is known to have. One of the key functions of ZDHHC11 is its role in cell signaling, specifically in the regulation of cell growth and differentiation.

ZDHHC11 has been shown to play a role in the regulation of cell proliferation and cell differentiation. It has been shown to be involved in the development and maintenance of tissues, such as the brain and heart. It has also been shown to be involved in the regulation of cell survival and cell death.

In addition to its role in cell signaling, ZDHHC11 is also of interest as a potential drug target. Its unique structure and the functions it is known to have make it an attractive target for drug development. One of the key advantages of ZDHHC11 as a drug target is its stability, as studies have shown that it is resistant to many common drugs and treatments.

Another potential advantage of ZDHHC11 as a drug target is its expression pattern. It has been shown to be expressed in various tissues of the human body, including the brain, heart, and pancreas. This makes it an attractive target for drugs that can selectively target this protein in these tissues.

In conclusion, ZDHHC11 is a protein that is of interest as a potential drug target or biomarker due to its unique structure and the functions it is known to have. Its role in cell signaling and its stability make it an attractive target for drug development. Further research is needed to fully understand the functions of ZDHHC11 and its potential as a drug target.

Protein Name: Zinc Finger DHHC-type Containing 11

Functions: Endoplasmic reticulum-localized palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates and be involved in a variety of cellular processes (By similarity). Has a palmitoyltransferase activity toward NCDN and regulates NCDN association with endosome membranes through this palmitoylation (By similarity). May play a role in cell proliferation (PubMed:28331227)

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