Zinc Finger and AN1-Type Domain 5: Potential Drug Targets and Biomarkers

Target Name: ZFAND5

NCBI ID: G7763

Zinc Finger and AN1-Type Domain 5: Potential Drug Targets and Biomarkers

Zinc Finger and AN1-Type Domain 5 (ZFAND5) are a type of gene that has been identified as a potential drug target and biomarker. ZFAND5 is a protein that is expressed in various tissues and cells throughout the body, including the brain, heart, and kidneys. It is made up of 21 amino acids and has a unique structure that is composed of a zinc finger and an AN1-type domain.

The zinc finger is a type of protein that is characterized by the presence of a zinc atom on the C-end. This type of protein is known for its ability to interact with other proteins and molecules, and it is believed to play a role in various cellular processes, including cell signaling and regulation. The AN1-type domain is a type of protein that is characterized by the presence of an AN1-type switch, which is a mechanism that allows the protein to switch between different forms.

Research has shown that ZFAND5 is involved in a number of different processes in the body, including the regulation of inflammation, the development and maintenance of blood vessels, and the regulation of ion and water balance. It is also thought to be involved in the development and progression of a number of diseases, including cancer.

One of the reasons why ZFAND5 has been identified as a potential drug target is its involvement in the regulation of inflammation. Chronic inflammation is associated with a number of diseases, including heart disease, cancer, and autoimmune disorders. Researchers have shown that ZFAND5 is involved in the regulation of inflammation by controlling the activity of various cellular signaling pathways.

In addition to its involvement in inflammation, ZFAND5 is also thought to be involved in the regulation of blood vessels. Researchers have shown that ZFAND5 is expressed in the endothelial cells that line the blood vessels, and that it is involved in the regulation of the growth and differentiation of these cells. This may be important for the development of cardiovascular disease.

Another potential drug target for ZFAND5 is its involvement in the regulation of ion and water balance. Many cells in the body need to maintain a specific balance of ions and water in order to function properly, and ZFAND5 is thought to be involved in this process. Researchers have shown that ZFAND5 is involved in the regulation of the activity of various ion channels, including those that control the movement of calcium and potassium ions into and out of cells. This may be important for a number of different processes in the body, including muscle and nerve function.

In conclusion, ZFAND5 is a protein that has been identified as a potential drug target and biomarker. Its unique structure and involvement in a number of different processes in the body make it an attractive target for research and development of new treatments. Further research is needed to fully understand the role of ZFAND5 in the regulation of inflammation, blood vessels, and ion and water balance, and to determine its potential as a drug.

Protein Name: Zinc Finger AN1-type Containing 5

Functions: Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation

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