Target Name: ZIC4
NCBI ID: G84107
Other Name(s): Zic family member 4 | zinc finger protein of the cerebellum 4 | Zinc finger protein ZIC 4 (isoform 3) | Zinc family member 4 protein HZIC4 | Zinc finger protein ZIC 4 | Zic family member 4, transcript variant 3 | ZIC4_HUMAN | zinc family member 4 protein HZIC4 | ZIC4 variant 3 | Zinc finger protein of the cerebellum 4

ZIC4: A Protein Regulator of Cell Growth and Differentiation

ZIC4, also known as Zic family member 4, is a protein that is expressed in various tissues of the body. It is a key regulator of cell growth and differentiation, and is involved in the development and maintenance of tissues such as the brain, heart, and lungs. ZIC4 has also been shown to play a role in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a result, ZIC4 has potential as a drug target or biomarker.

The Zic family of proteins is a group of non-coding RNAs that are characterized by their ability to interact with the protein Zic. Zic is a transmembrane protein that is involved in several signaling pathways, including the TGF-β pathway. TGF-β is a critical pathway that regulates cell growth, differentiation, and survival, and is involved in the development and maintenance of tissues such as the brain, heart, and lungs. Zic is a key regulator of TGF-β signaling, and is involved in the development and maintenance of these tissues.

ZIC4 is a key component of the TGF-β pathway. It is a critical regulator of TGF-β signaling, and is involved in the development and maintenance of tissues such as the brain, heart, and lungs. ZIC4 plays a role in the regulation of cell proliferation, differentiation, and survival. It is also involved in the regulation of cell-cell adhesion, and is thought to play a role in the development and maintenance of tissues such as the placenta and the immune system.

In addition to its role in TGF-β signaling, ZIC4 is also involved in the regulation of several other signaling pathways. It is involved in the regulation of cell adhesion, and is thought to play a role in the development and maintenance of tissues such as the brain and the heart. ZIC4 is also involved in the regulation of the Wnt signaling pathway, and is thought to play a role in the development and maintenance of tissues such as the lung and the nervous system.

ZIC4 has been shown to be involved in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that high levels of ZIC4 are associated with poor prognosis in patients with pancreatic cancer. Additionally, research has suggested that ZIC4 may play a role in the development and progression of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

As a result of its involvement in several signaling pathways, ZIC4 has potential as a drug target or biomarker. Researchers are currently working to develop small molecules that can inhibit the activity of ZIC4, with the goal of using these molecules as therapeutic agents for a variety of diseases. For example, researchers have developed small molecules that can inhibit the activity of ZIC4 in the context of cancer, neurodegenerative diseases, and autoimmune disorders. These small molecules are currently being tested in clinical trials to determine their safety and effectiveness as therapeutic agents.

In conclusion, ZIC4 is a protein that is involved in several signaling pathways, including TGF-β, cell adhesion, and Wnt. It has been shown to play a role in the development and maintenance of tissues such as the brain, heart, and lungs, and is also involved in the regulation of cell proliferation, differentiation, and survival. As a result, ZIC4 has potential as a drug target or biomarker for a variety of diseases. Researchers are currently working to develop small molecules that can inhibit the activity of ZIC4, with the goal of using these molecules as therapeutic agents for a variety of diseases.

Protein Name: Zic Family Member 4

Functions: Binds to DNA

More Common Targets

ZIC5 | ZIK1 | ZIM2 | ZIM3 | Zinc finger protein GLI | ZKSCAN1 | ZKSCAN2 | ZKSCAN3 | ZKSCAN4 | ZKSCAN5 | ZKSCAN7 | ZKSCAN8 | ZKSCAN8P1 | ZMAT1 | ZMAT2 | ZMAT3 | ZMAT4 | ZMAT5 | ZMIZ1 | ZMIZ1-AS1 | ZMIZ2 | ZMPSTE24 | ZMYM1 | ZMYM2 | ZMYM3 | ZMYM4 | ZMYM4-AS1 | ZMYM5 | ZMYM6 | ZMYND10 | ZMYND11 | ZMYND12 | ZMYND15 | ZMYND19 | ZMYND8 | ZNF10 | ZNF100 | ZNF101 | ZNF106 | ZNF107 | ZNF112 | ZNF114 | ZNF117 | ZNF12 | ZNF121 | ZNF124 | ZNF131 | ZNF132 | ZNF133 | ZNF134 | ZNF135 | ZNF136 | ZNF137P | ZNF138 | ZNF14 | ZNF140 | ZNF141 | ZNF142 | ZNF143 | ZNF146 | ZNF148 | ZNF154 | ZNF155 | ZNF157 | ZNF16 | ZNF160 | ZNF165 | ZNF169 | ZNF17 | ZNF174 | ZNF175 | ZNF177 | ZNF18 | ZNF180 | ZNF181 | ZNF182 | ZNF184 | ZNF185 | ZNF189 | ZNF19 | ZNF195 | ZNF197 | ZNF2 | ZNF20 | ZNF200 | ZNF202 | ZNF204P | ZNF205 | ZNF205-AS1 | ZNF207 | ZNF208 | ZNF209P | ZNF211 | ZNF212 | ZNF213 | ZNF213-AS1 | ZNF214 | ZNF215 | ZNF217 | ZNF219