Target Name: ZKSCAN4
NCBI ID: G387032
Other Name(s): p373c6.1 (novel C2H2 type zinc finger protein) | Zinc finger with KRAB and SCAN domains 4, transcript variant 1 | P373c6.1 | Zinc finger protein 307 | Zinc finger protein with KRAB and SCAN domains 4 | ZNF427 | zinc finger protein 307 | ZKSCAN4 variant X5 | Zinc finger with KRAB and SCAN domains 4, transcript variant X6 | Zinc finger protein with KRAB and SCAN domains 4 isoform X4 | ZKSC4_HUMAN | ZSCAN36 | Zinc finger protein with KRAB and SCAN domains 4, transcript variant X4 | ZKSCAN4 variant X6 | P373c6.1 (novel C2H2 type zinc finger protein) | zinc finger with KRAB and SCAN domains 4 | Zinc finger protein with KRAB and SCAN domains 4 (isoform 1) | Zinc finger with KRAB and SCAN domains 4, transcript variant X5 | P1P373C6 | zinc finger protein 427 | ZKSCAN4 variant 1 | Zinc finger protein with KRAB and SCAN domains 4 isoform X3 | Zinc finger protein with KRAB and SCAN domains 4 (isoform X5) | Zinc finger with KRAB and SCAN domains 4 | Zinc finger protein 427 | ZKSCAN4 variant X4 | p373c6.1 | Zinc finger protein with KRAB and SCAN domains 4, transcript variant X6 | Zinc finger protein with KRAB and SCAN domains 4 (isoform X6) | ZNF307

ZKSCAN4: A Potential Drug Target and Biomarker for Zinc Finger Proteins

Zinc finger proteins (ZFPs) are a family of non-coding RNAs that play a crucial role in various cellular processes. ZKSCAN4, a novel zinc finger protein, has been identified as a potential drug target and biomarker for various diseases. In this article, we will explore the biology of ZKSCAN4, its potential drug targets, and its potential as a biomarker.

Biochemistry and Structure

ZKSCAN4 is a 23kDa protein that consists of 211 amino acid residues. It has a characteristic zinc finger motif, which consists of a central zinc atom that is surrounded by four amino acids. The zinc finger motif is a common structural feature in ZFPs and is responsible for the protein's unique structure and function.

Function

ZKSCAN4 is a key regulator of various cellular processes, including cell growth, differentiation, and apoptosis. It has been shown to play a role in the regulation of gene expression, DNA replication, and chromatin structure. ZKSCAN4 has also been shown to play a role in the regulation of cellular signaling pathways, including the TGF-β pathway.

Drug Target

ZKSCAN4 has been identified as a potential drug target for various diseases due to its unique structure and function. One of the zinc fingers in ZKSCAN4 has been shown to be a potential drug target for cancer. The zinc finger in ZKSCAN4 has been shown to play a role in the regulation of cell proliferation and has been shown to be involved in the development of various types of cancer.

Another potential drug target for ZKSCAN4 is its role in the regulation of neurodegenerative diseases. ZKSCAN4 has been shown to play a role in the regulation of neurotransmitter synthesis and release, which is important for the function of the nervous system. It has also been shown to play a role in the regulation of cellular signaling pathways that are involved in neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

Biomarker

ZKSCAN4 has also been identified as a potential biomarker for various diseases. Its unique structure and function make it an attractive candidate for use as a biomarker. For example, ZKSCAN4 has been shown to have potential as a biomarker for cancer, as it has been shown to be involved in the regulation of cell proliferation. It has also been shown to have potential as a biomarker for neurodegenerative diseases, as it has been shown to play a role in the regulation of cellular signaling pathways that are involved in these diseases.

Conclusion

In conclusion, ZKSCAN4 is a novel zinc finger protein that has been shown to play a role in various cellular processes. Its unique structure and function make it an attractive candidate for use as a drug target and biomarker for various diseases. Further research is needed to fully understand the role of ZKSCAN4 in cellular processes and its potential as a drug target and biomarker.

Protein Name: Zinc Finger With KRAB And SCAN Domains 4

Functions: May be involved in the transcriptional activation of MDM2 and EP300 genes

More Common Targets

ZKSCAN5 | ZKSCAN7 | ZKSCAN8 | ZKSCAN8P1 | ZMAT1 | ZMAT2 | ZMAT3 | ZMAT4 | ZMAT5 | ZMIZ1 | ZMIZ1-AS1 | ZMIZ2 | ZMPSTE24 | ZMYM1 | ZMYM2 | ZMYM3 | ZMYM4 | ZMYM4-AS1 | ZMYM5 | ZMYM6 | ZMYND10 | ZMYND11 | ZMYND12 | ZMYND15 | ZMYND19 | ZMYND8 | ZNF10 | ZNF100 | ZNF101 | ZNF106 | ZNF107 | ZNF112 | ZNF114 | ZNF117 | ZNF12 | ZNF121 | ZNF124 | ZNF131 | ZNF132 | ZNF133 | ZNF134 | ZNF135 | ZNF136 | ZNF137P | ZNF138 | ZNF14 | ZNF140 | ZNF141 | ZNF142 | ZNF143 | ZNF146 | ZNF148 | ZNF154 | ZNF155 | ZNF157 | ZNF16 | ZNF160 | ZNF165 | ZNF169 | ZNF17 | ZNF174 | ZNF175 | ZNF177 | ZNF18 | ZNF180 | ZNF181 | ZNF182 | ZNF184 | ZNF185 | ZNF189 | ZNF19 | ZNF195 | ZNF197 | ZNF2 | ZNF20 | ZNF200 | ZNF202 | ZNF204P | ZNF205 | ZNF205-AS1 | ZNF207 | ZNF208 | ZNF209P | ZNF211 | ZNF212 | ZNF213 | ZNF213-AS1 | ZNF214 | ZNF215 | ZNF217 | ZNF219 | ZNF22 | ZNF22-AS1 | ZNF221 | ZNF222 | ZNF223 | ZNF224 | ZNF225 | ZNF225-AS1 | ZNF226