Target Name: ZFY
NCBI ID: G7544
Other Name(s): Zinc finger Y-chromosomal protein | Zinc finger protein, Y-linked | ZFY variant 1 | OTTHUMP00000034366 | Zinc finger protein Y-linked, transcript variant 1 | ZFY_HUMAN | MGC138710 | Zinc finger Y-chromosomal protein (isoform 1) | zinc finger protein Y-linked | ZNF911

Zinc Finger Y-Chromosomal Protein (ZFY)

Zinc Finger Y-Chromosomal Protein (ZFY) is a protein that is expressed in almost all human tissues and is involved in a wide range of cellular processes. ZFY is also known as ZNF2, which is a key regulator of the Y-chromosome.

The ZFY gene was first identified in 2003 and has since been extensively studied. It is a member of the TY gene family, which is responsible for the development and maintenance of testicular tissue. ZFY is expressed in a variety of tissues, including testes, ovaries , brain, heart, and skeletal muscles.

One of the key functions of ZFY is its role in regulating the expression of other genes. It has been shown to play a role in the regulation of cell proliferation, differentiation, and survival. ZFY has also been shown to interact with a variety of transcription factors, including DNMT1 and p53.

In addition to its role in gene regulation, ZFY is also a potential drug target. Several studies have suggested that ZFY may be a useful target for small molecule inhibitors, such as inhibitors of DNA binding or RNA binding. ZFY has also been shown to interact with proteins that are known to be involved in cancer, including the androgen receptor and the Ku70 gene.

Another potential application of ZFY is its use as a biomarker. The expression of ZFY has been shown to be altered in a variety of diseases, including cancer, neurodegenerative diseases, and genetic disorders. For example, a study published in the journal Oncogene found that ZFY was expressed in human tissues and was associated with poor prognosis in patients with pancreatic cancer.

In conclusion, Zinc Finger Y-Chromosomal Protein (ZFY) is a protein that is involved in a wide range of cellular processes and has been shown to play a role in the regulation of gene expression and cell survival. Its potential as a drug target and biomarker make it an attractive target for further research. Further studies are needed to fully understand the role of ZFY in disease and to develop effective treatments.

Protein Name: Zinc Finger Protein Y-linked

Functions: Probable transcriptional activator. Binds to the consensus sequence 5'-AGGCCY-3'

More Common Targets

ZFYVE1 | ZFYVE16 | ZFYVE19 | ZFYVE21 | ZFYVE26 | ZFYVE27 | ZFYVE28 | ZFYVE9 | ZFYVE9P1 | ZG16 | ZG16B | ZGLP1 | ZGPAT | ZGRF1 | ZHX1 | ZHX1-C8orf76 | ZHX2 | ZHX3 | ZIC1 | ZIC2 | ZIC3 | ZIC4 | ZIC5 | ZIK1 | ZIM2 | ZIM3 | Zinc finger protein GLI | ZKSCAN1 | ZKSCAN2 | ZKSCAN3 | ZKSCAN4 | ZKSCAN5 | ZKSCAN7 | ZKSCAN8 | ZKSCAN8P1 | ZMAT1 | ZMAT2 | ZMAT3 | ZMAT4 | ZMAT5 | ZMIZ1 | ZMIZ1-AS1 | ZMIZ2 | ZMPSTE24 | ZMYM1 | ZMYM2 | ZMYM3 | ZMYM4 | ZMYM4-AS1 | ZMYM5 | ZMYM6 | ZMYND10 | ZMYND11 | ZMYND12 | ZMYND15 | ZMYND19 | ZMYND8 | ZNF10 | ZNF100 | ZNF101 | ZNF106 | ZNF107 | ZNF112 | ZNF114 | ZNF117 | ZNF12 | ZNF121 | ZNF124 | ZNF131 | ZNF132 | ZNF133 | ZNF134 | ZNF135 | ZNF136 | ZNF137P | ZNF138 | ZNF14 | ZNF140 | ZNF141 | ZNF142 | ZNF143 | ZNF146 | ZNF148 | ZNF154 | ZNF155 | ZNF157 | ZNF16 | ZNF160 | ZNF165 | ZNF169 | ZNF17 | ZNF174 | ZNF175 | ZNF177 | ZNF18 | ZNF180 | ZNF181 | ZNF182 | ZNF184 | ZNF185