Target Name: ZFAND4
NCBI ID: G93550
Other Name(s): AN1, ubiquitin-like, homolog | ZFAND4 variant 1 | Zinc finger AN1-type containing 4, transcript variant 1 | AN1-type zinc finger and ubiquitin domain-containing protein 1 | ANUBL1 | zinc finger, AN1-type domain 4 | ZFAN4_HUMAN | AN1-type zinc finger and ubiquitin domain-containing protein-like 1 | ZFAND4 variant 4 | zinc finger AN1-type containing 4 | AN1-type zinc finger protein 4 | AN1-type zinc finger protein 4 (isoform b) | Zinc finger AN1-type containing 4, transcript variant 4 | AN1-type zinc finger protein 4 (isoform a)

ZFAND4: A Potential Drug Target and Biomarker for the Treatment of Anemia and Chronic Kidney Disease

Abstract:

ZFAND4, a member of the ZNF2 gene family, has been identified as a potential drug target and biomarker for the treatment of anemia and chronic kidney disease. The study of ZFAND4 has significant implications for the development of new therapeutic strategies for these conditions.

Introduction:

Anemia and chronic kidney disease are significant public health issues that affect millions of people worldwide. Anemia is a condition that not only affects the individual but also the entire population, leading to increased risk of infections, impaired immune function, and increased morbidity. Chronic kidney disease (CKD) is a progressive disease that can progress to end-stage renal failure, leading to significant morbidity and mortality. The development of new therapeutic strategies is crucial for the treatment of these conditions.

The ZFAND4 gene:

The ZFAND4 gene is a member of the ZNF2 gene family, which is known for its role in the development and maintenance of tissues, including the immune system, eye, and kidney. The ZFAND4 gene has been identified as a potential drug target and biomarker for the treatment of anemia and CKD due to its unique structure and expression patterns.

Functional analysis of ZFAND4:

The ZFAND4 gene has been shown to play a significant role in the development and maintenance of tissues. ZFAND4 has been shown to be involved in the development and maintenance of immune cells, including T cells and natural killer cells. ZFAND4 has also been shown to be involved in the development and maintenance of tissues that are critical for the function of the kidneys, including the development and maintenance of glomeruli and interstitial tissues.

In addition to its role in the development and maintenance of tissues, ZFAND4 has also been shown to play a significant role in the regulation of gene expression. ZFAND4 has been shown to be involved in the regulation of the expression of genes that are involved in the development and maintenance of tissues, including those involved in the immune system, eye, and kidney.

Potential drug target:

The ZFAND4 gene has significant potential as a drug target for the treatment of anemia and CKD due to its involvement in the development and maintenance of tissues that are critical for the function of the kidneys. Anemia is a condition that can lead to decreased red blood cells (RBCs) and increased risk of infections, impair immune function, and increased morbidity. Chronic kidney disease (CKD) is a progressive disease that can progress to end-stage renal failure, leading to significant morbidity and mortality.

The development of new therapeutic strategies for anemia and CKD is crucial for the treatment of these conditions. The ZFAND4 gene has the potential to be a drug target for the treatment of these conditions due to its unique structure and expression patterns.

Biomarker:

The ZFAND4 gene has also been shown to be involved in the regulation of gene expression, which could be used as a biomarker for the diagnosis and monitoring of anemia and CKD. The development of new diagnostic tests and biomarkers for anemia and CKD could have a significant impact on the diagnosis and treatment of these conditions.

Conclusion:

The ZFAND4 gene has significant potential as a drug target and biomarker for the treatment of anemia and CKD due to its involvement in the development and maintenance of tissues that are critical for the function of the kidneys. Further research is needed to confirm its potential as a drug target and biomarker for the treatment of these conditions.

Protein Name: Zinc Finger AN1-type Containing 4

More Common Targets

ZFAND5 | ZFAND6 | ZFAS1 | ZFAT | ZFAT-AS1 | ZFC3H1 | ZFHX2 | ZFHX3 | ZFHX4 | ZFHX4-AS1 | ZFP1 | ZFP14 | ZFP2 | ZFP28 | ZFP28-DT | ZFP3 | ZFP30 | ZFP36 | ZFP36L1 | ZFP36L2 | ZFP37 | ZFP41 | ZFP42 | ZFP57 | ZFP62 | ZFP64 | ZFP64P1 | ZFP69 | ZFP69B | ZFP82 | ZFP90 | ZFP91 | ZFP91-CNTF | ZFP92 | ZFPL1 | ZFPM1 | ZFPM2 | ZFPM2-AS1 | ZFR | ZFR2 | ZFTA | ZFTRAF1 | ZFX | ZFX-AS1 | ZFY | ZFYVE1 | ZFYVE16 | ZFYVE19 | ZFYVE21 | ZFYVE26 | ZFYVE27 | ZFYVE28 | ZFYVE9 | ZFYVE9P1 | ZG16 | ZG16B | ZGLP1 | ZGPAT | ZGRF1 | ZHX1 | ZHX1-C8orf76 | ZHX2 | ZHX3 | ZIC1 | ZIC2 | ZIC3 | ZIC4 | ZIC5 | ZIK1 | ZIM2 | ZIM3 | Zinc finger protein GLI | ZKSCAN1 | ZKSCAN2 | ZKSCAN3 | ZKSCAN4 | ZKSCAN5 | ZKSCAN7 | ZKSCAN8 | ZKSCAN8P1 | ZMAT1 | ZMAT2 | ZMAT3 | ZMAT4 | ZMAT5 | ZMIZ1 | ZMIZ1-AS1 | ZMIZ2 | ZMPSTE24 | ZMYM1 | ZMYM2 | ZMYM3 | ZMYM4 | ZMYM4-AS1 | ZMYM5 | ZMYM6 | ZMYND10 | ZMYND11 | ZMYND12 | ZMYND15