ZDHHC11B: A Potential Drug Target and Biomarker (G653082)

Target Name: ZDHHC11B

NCBI ID: G653082

ZDHHC11B: A Potential Drug Target and Biomarker

Introduction

ZDHHC11B is a gene that encodes a protein known as ZDHHC11B, which is a member of the Zinc Finger N-Terminal Hydrolase (ZFNTH) family. ZFNTHs are a group of enzymes that belong to the N-terminal Zinc Finger gene family, which is characterized by the presence of a zinc finger protein that consists of a N-terminal Zinc Finger and a C-terminal domain. ZDHHC11B is a unique gene because it is not characterized by any known function or activity. However, its sequence similarity to other ZFNTHs has led to the possibility that it may have some novel function.

The ZFNTH family is a diverse group of enzymes that are involved in a variety of cellular processes. Many of these enzymes are involved in signaling pathways, including cell growth, differentiation, and apoptosis. ZFNTHs also play important roles in intracellular signaling, including the regulation of ion channels, protein kinase, and transcriptional factors.

One of the unique features of ZDHHC11B is its unusual gene structure. Unlike most genes, ZDHHC11B does not have a clear coding region or a putative protein domain. Instead, it has a single exon that is splice-able with other genes. This is unusual because most genes have a larger coding region and a clear protein domain. The lack of a clear coding region and protein domain suggests that ZDHHC11B may not have a typical ZFNTH function.

The lack of information about ZDHHC11B function has made it difficult to determine its potential as a drug target or biomarker. However, its sequence similarity to other ZFNTHs has led to the possibility that it may have some novel function. For example, ZDHHC11B may be involved in the regulation of intracellular signaling pathways, including the regulation of cell growth, differentiation, and apoptosis. It may also be involved in the regulation of ion channels, protein kinase, or transcriptional factors.

In conclusion, ZDHHC11B is an interesting gene that has not been characterized by any known function or activity. Its sequence similarity to other ZFNTHs has led to the possibility that it may have some novel function, including its involvement in intracellular signaling pathways and its potential as a drug target or biomarker. Further research is needed to determine the true function of ZDHHC11B and its potential implications for human health.

Protein Name: Zinc Finger DHHC-type Containing 11B

Functions: Probable palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates and be involved in a variety of cellular processes (By similarity). May play a role in cell proliferation (PubMed:28331227)

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