ZBTB42: A Drug Target / Disease Biomarker (G100128927)

Target Name: ZBTB42

NCBI ID: G100128927

ZBTB42: A Drug Target / Disease Biomarker

ZBTB42 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the Zonulin-protein family, which is known for their role in regulating cell-cell adhesion and signaling. ZBTB42 has been shown to play a role in a variety of physiological processes, including cell signaling, neurodegeneration, and fibrosis. As a result, ZBTB42 has potential as a drug target or biomarker in a variety of diseases.

One of the key functions of ZBTB42 is its role in cell signaling. It is a potent positive regulator of the protein F-actinin, which is involved in cell adhesion and migration. F-actinin is a protein that is expressed in various tissues, including the brain, and is known for its role in the regulation of neural circuits. By regulating F-actinin, ZBTB42 helps to control the movement of cells and the formation of tissues.

Another function of ZBTB42 is its role in neurodegeneration. neurodegeneration is a condition in which the brain and other nervous system cells die or are damaged, leading to a range of symptoms, including cognitive decline, weakness, and loss of function. ZBTB42 has been shown to be involved in the regulation of neurodegeneration, and may be a potential drug target for treatments of neurodegenerative diseases.

In addition to its role in cell signaling and neurodegeneration, ZBTB42 is also involved in the regulation of fibrosis. Fibrosis is a condition in which cells become abnormally organized and produce an excessive amount of extracellular matrix (ECM) material. This can lead to a range of diseases, including heart failure, cancer, and chronic obstructive pulmonary disease (COPD). ZBTB42 has been shown to be involved in the regulation of fibrosis, and may be a potential biomarker for the diagnosis and treatment of fibrosities.

Overall, ZBTB42 is a protein that plays a critical role in a variety of physiological processes in the body. Its functions in cell signaling, neurodegeneration, and fibrosis make it a potential drug target or biomarker in a variety of diseases. Further research is needed to fully understand the role of ZBTB42 in these processes and its potential as a therapeutic agent.

Protein Name: Zinc Finger And BTB Domain Containing 42

Functions: Transcriptional repressor. Specifically binds DNA and probably acts by recruiting chromatin remodeling multiprotein complexes

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