Target Name: GPR139
NCBI ID: G124274
Other Name(s): Probable G-protein coupled receptor 139 | G protein-coupled receptor PGR3 | GPR139 variant 1 | G-protein-coupled receptor PGR3 | G protein-coupled receptor 139 (GPR139) | G(q)-coupled orphan receptor GPRg1 | G protein-coupled receptor 139, transcript variant 1 | G protein-coupled receptor 139 | GP139_HUMAN | Probable G-protein coupled receptor 139 (isoform 1) | g(q)-coupled orphan receptor GPRg1 | GPRg1 | PGR3

Study of GPR139: GPCR Protein Involved in Many Physiological Processes

GPR139 is a protein that is expressed in many different tissues throughout the body. It is a member of the G-protein coupled receptor (GPCR) family, which is a large superfamily of transmembrane proteins that play a key role in cellular signaling. GPR139 is one of the most well-studied GPCR proteins, and it is known for its role in a wide range of physiological processes, including sensory perception, neurotransmission, and hormone signaling.

GPR139 is a receptor that is expressed in the central nervous system (CNS), and it is thought to play a key role in the function of the nervous system. It is found in the postsynaptic density of neurons, which is the protein that makes up the synapse, the site where nerve signals are passed on to the next neuron. GPR139 is also expressed in other tissues, including the retina, and it is thought to be involved in the sense of touch.

One of the key functions of GPR139 is its role in sensory perception. The sense of touch is mediated by the posterior cingulate cortex, which is a region of the brain that is responsible for processing sensory information. GPR139 is thought to be involved in the development and maintenance of the sense of touch, by interacting with the postsynaptic density of neurons and other cells in the CNS.

Another function of GPR139 is its role in neurotransmission. Neurotransmitters are chemical messengers that are used by neurons to communicate with each other. GPR139 is thought to be involved in the release and reception of neurotransmitters, by interacting with postsynaptic density proteins and other cell types.

GPR139 is also involved in the regulation of hormone signaling. Hormones are chemical messengers that are produced by glands and used to regulate various physiological processes, including growth, development, and metabolism. GPR139 is thought to be involved in the regulation of hormone signaling, by interacting with the hormone receptors that are found in many different tissues.

In addition to its role in sensory perception, neurotransmission, and hormone signaling, GPR139 is also involved in the regulation of many other physiological processes. For example, it is thought to be involved in the regulation of blood pressure, and it is also involved in the regulation of body temperature. GPR139 may also be involved in the regulation of appetite and metabolism, and it is thought to be involved in the development and maintenance of the immune system.

Despite its many functions, GPR139 is not yet a well-studied drug target. Many researchers are interested in studying GPR139, because they believe that it may be a useful target for the development of new drugs. For example, GPR139 has been shown to be involved in the regulation of a wide range of physiological processes, and it is thought to be involved in the development and maintenance of the nervous system. This suggests that GPR139 may be a useful target for the development of drugs that can modulate these processes.

In conclusion, GPR139 is a protein that is expressed in many different tissues throughout the body. It is a member of the GPCR family, and it is involved in a wide range of physiological processes, including sensory perception, neurotransmission, and hormone signaling. GPR139 may be a useful drug target, due to its involvement in these processes, and it is a focus of ongoing research in the field of GPCR biology.

Protein Name: G Protein-coupled Receptor 139

Functions: Orphan receptor. Seems to act through a G(q/11)-mediated pathway

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