Target Name: GPR153
NCBI ID: G387509
Other Name(s): G protein-coupled receptor 153 | GP153_HUMAN | Probable G-protein coupled receptor 153 | PGR1 | G-protein coupled receptor PGR1 | DKFZp762B2210

GPR153: A GPCR Involved in Neurotransmission, Sensory Perception and Hormone Signaling

G protein-coupled receptors (GPCRs) are a family of transmembrane proteins that play a crucial role in cellular signaling. GPCRs are involved in various physiological processes, including sensory perception, neurotransmission, and hormone signaling. GPCRs are also known as GPRs, and their You can number is determined by the number of constant and variable regions they contain. GPR153 is a GPCR that is expressed in various tissues of the body and is involved in several physiological processes. In this article, we will discuss GPR153, its function, potential drug targets, and potential biomarkers.

GPR153 is a 12-kDa protein that is expressed in the brain, heart, skeletal muscles, and other tissues of the body. It is a member of the GPCR family and is characterized by the presence of a catalytic alpha-helices and a transmembrane region . GPR153 is involved in several physiological processes, including neurotransmission, sensory perception, and hormone signaling.

GPR153 is involved in neurotransmission
GPR153 is involved in neurotransmission by mediating the release of neurotransmitters, such as dopamine and serotonin, from axon terminals. GPR153 is also involved in the modulation of neurotransmitter release by various signaling molecules, including GABA and glutamate. These signaling pathways are important for the proper functioning of the nervous system and are implicated in various neurological disorders, including Parkinson's disease, Alzheimer's disease, and schizophrenia.

GPR153 is involved in sensory perception
GPR153 is involved in sensory perception by mediating the transmission of sensory information from the senses to the brain. GPR153 is involved in the transmission of information from the skin, hair, and muscles to the brain, allowing individuals to perceive touch, pain, and other sensations. GPR153 is also involved in the regulation of pain perception and has been implicated in the development of chronic pain conditions.

GPR153 is involved in hormone signaling
GPR153 is involved in hormone signaling by mediating the intake of hormones by cells. GPR153 is involved in the regulation of glucose and insulin signaling, as well as the intake of sex hormones. These signaling pathways are important for the proper functioning of various physiological processes and are implicated in various hormone-related disorders, including obesity, type 2 diabetes, and menstrual disorders.

GPR153 is a potential drug target
GPR153 is a potential drug target due to its involvement in several physiological processes. GPR153 can be targeted by small molecules, such as drugs that can modulate its activity, such as inhibitors of GABA receptors or modulators of the activity of GPCRs. Additionally, GPR153 can be targeted by antibodies that recognize and bind to its specific epitope.

In conclusion, GPR153 is a GPCR that is involved in several physiological processes, including neurotransmission, sensory perception, and hormone signaling. Its function makes it a potential drug target, and its study may provide new insights into the development of new treatments for various neurological and psychiatric disorders. Further research is needed to fully understand the role of GPR153 in these processes and to develop effective treatments.

Protein Name: G Protein-coupled Receptor 153

Functions: Orphan receptor

More Common Targets

GPR155 | GPR156 | GPR157 | GPR158 | GPR158-AS1 | GPR15LG | GPR160 | GPR161 | GPR162 | GPR17 | GPR171 | GPR173 | GPR174 | GPR176 | GPR179 | GPR18 | GPR180 | GPR182 | GPR183 | GPR19 | GPR199P | GPR20 | GPR21 | GPR22 | GPR25 | GPR26 | GPR27 | GPR3 | GPR31 | GPR32 | GPR33 | GPR34 | GPR35 | GPR37 | GPR37L1 | GPR39 | GPR4 | GPR42 | GPR45 | GPR50 | GPR52 | GPR55 | GPR6 | GPR61 | GPR62 | GPR63 | GPR65 | GPR68 | GPR75 | GPR75-ASB3 | GPR78 | GPR79 | GPR82 | GPR83 | GPR84 | GPR84-AS1 | GPR85 | GPR87 | GPR88 | GPR89A | GPR89B | GPRACR | GPRASP1 | GPRASP2 | GPRASP3 | GPRC5A | GPRC5B | GPRC5C | GPRC5D | GPRC5D-AS1 | GPRC6A | GPRIN1 | GPRIN2 | GPRIN3 | GPS, PLAT and transmembrane domain-containing protein | GPS1 | GPS2 | GPS2P1 | GPSM1 | GPSM2 | GPSM3 | GPT | GPT2 | GPX1 | GPX1P1 | GPX2 | GPX3 | GPX4 | GPX5 | GPX6 | GPX7 | GPX8 | GRAMD1A | GRAMD1B | GRAMD1C | GRAMD2A | GRAMD2B | GRAMD4 | GRAMD4P2 | GRAMD4P5