Target Name: GPHB5
NCBI ID: G122876
Other Name(s): Glycoprotein hormone subunit beta 5 | GPB5 | GPHB5_HUMAN | glycoprotein hormone beta subunit | Thyrostimulin subunit beta | B5 | Glycoprotein hormone beta 5 | glycoprotein hormone subunit beta 5 | thyrostimulin subunit beta | glycoprotein beta 5 | glycoprotein hormone beta 5 | Thyrostimulin beta subunit | Glycoprotein hormone beta-5 | ZLUT1

GPHB5 Regulates Ion Channels, Neuronal Excitability and Cell Survival

GPHB5, also known as Glycoprotein Hormone Subunit Beta 5, is a protein that is expressed in various tissues throughout the body. It is a member of the Glycoprotein Hormone (GPH) family, which is a subfamily of the protein transmembrane receptor family. GPHs are involved in the regulation of a wide range of physiological processes, including growth, development, and reproduction.

GPHB5 is a 13 kDa protein that is expressed in the brain, heart, liver, and kidneys. It is involved in the regulation of ion channels, which are responsible for the flow of electrical signals through cells. GPHB5 is also involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed.

One of the key functions of GPHB5 is its role in the regulation of neuronal excitability. GPHB5 is involved in the regulation of the ion channels that are responsible for the flow of electrical signals through neurons. This is important for the proper function of the nervous system , as changes in the levels of electrical signals can have a significant impact on brain function.

Another important function of GPHB5 is its role in the regulation of inflammation. GPHB5 is involved in the regulation of the production of pro-inflammatory cytokines, which are important for the recruitment of immune cells to the site of an injury or infection. This is important for the proper functioning of the immune system, as chronic inflammation can contribute to a wide range of diseases, including heart disease, diabetes, and cancer.

GPHB5 is also involved in the regulation of cell survival. GPHB5 is a negative regulator of the survival protein, which is a protein that is involved in the regulation of cell survival. This is important for the proper functioning of cells, as changes in the levels of this protein can have a significant impact on cellular processes, including the regulation of cell death.

GPHB5 is also involved in the regulation of the development and progression of tissues. GPHB5 is involved in the regulation of the production of cell types, as well as the regulation of their distribution throughout the body. This is important for the proper functioning of tissues, as changes in the levels of this protein can have a significant impact on cellular processes.

GPHB5 is also involved in the regulation of the regulation of DNA replication. GPHB5 is involved in the regulation of the production of DNA replication proteins, which are important for the replication of genetic material. This is important for the proper functioning of cells, as changes in the levels of this protein can have a significant impact on cellular processes.

GPHB5 is also involved in the regulation of the regulation of gene expression. GPHB5 is involved in the regulation of the translation of DNA into proteins, which is important for the proper functioning of cells. This is important for the regulation of cellular processes, including the regulation of cell death.

GPHB5 is also involved in the regulation of the regulation of cell signaling pathways. GPHB5 is involved in the regulation of the signaling pathways that are responsible for the regulation of cellular processes. This is important for the proper functioning of cells, as changes in the levels of this protein can have a significant impact on cellular processes.

GPHB5 is also involved in the regulation of the regulation of protein folding. GPHB5 is involved in the regulation of the folding of proteins, which is the process by which these proteins are produced from their amino acid sequence. This is important for the proper functioning of cells, as changes in the levels of this protein can have a significant impact on cellular processes.

GPHB5 is also involved in the regulation of the regulation of protein stability. GPHB5 is involved in the regulation of the stability of proteins, which is the process by which these proteins are protected from degradation. This is important for the proper functioning

Protein Name: Glycoprotein Hormone Subunit Beta 5

Functions: Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism

More Common Targets

GPHN | GPI | GPI transamidase complex | GPI-GlcNAc transferase complex | GPIHBP1 | GPKOW | GPLD1 | GPM6A | GPM6B | GPN1 | GPN2 | GPN3 | GPNMB | GPR101 | GPR107 | GPR108 | GPR119 | GPR12 | GPR132 | GPR135 | GPR137 | GPR137B | GPR137C | GPR139 | GPR141 | GPR142 | GPR143 | GPR146 | GPR148 | GPR149 | GPR15 | GPR150 | GPR151 | GPR152 | GPR153 | GPR155 | GPR156 | GPR157 | GPR158 | GPR158-AS1 | GPR15LG | GPR160 | GPR161 | GPR162 | GPR17 | GPR171 | GPR173 | GPR174 | GPR176 | GPR179 | GPR18 | GPR180 | GPR182 | GPR183 | GPR19 | GPR199P | GPR20 | GPR21 | GPR22 | GPR25 | GPR26 | GPR27 | GPR3 | GPR31 | GPR32 | GPR33 | GPR34 | GPR35 | GPR37 | GPR37L1 | GPR39 | GPR4 | GPR42 | GPR45 | GPR50 | GPR52 | GPR55 | GPR6 | GPR61 | GPR62 | GPR63 | GPR65 | GPR68 | GPR75 | GPR75-ASB3 | GPR78 | GPR79 | GPR82 | GPR83 | GPR84 | GPR84-AS1 | GPR85 | GPR87 | GPR88 | GPR89A | GPR89B | GPRACR | GPRASP1 | GPRASP2 | GPRASP3