GPC4: A Protein with Potential for Cancer, Cell Death and Tissue Formation

GPC4: A Protein with Potential for Cancer, Cell Death and Tissue Formation

GPC4, also known as secreted glypican-4, is a protein that is expressed in various tissues throughout the body. It is a member of the glypican family, which is a group of transmembrane proteins that are involved in cell signaling and tissue repair. GPC4 is unique because it is highly expressed in the placenta, which is a vital organ that plays a critical role in the development and maintenance of fetal tissue.

One of the key functions of GPC4 is its role in the regulation of cell proliferation. GPC4 has been shown to play a negative role in cell proliferation, by inhibiting the ability of cells to divide and grow. This is important because an imbalance in cell proliferation can lead to the development of cancer.

Another function of GPC4 is its role in the regulation of cell death. GPC4 has been shown to play a positive role in the regulation of cell death, by helping to ensure that cells die in a controlled and orderly manner. This is important because the regulation of cell death is critical for maintaining the health and function of tissues.

In addition to its functions in cell proliferation and cell death, GPC4 has also been shown to play a role in the regulation of tissue formation and maintenance. GPC4 has been shown to play a positive role in the regulation of tissue formation, by helping to ensure that new tissues are properly formed and maintained. This is important because a healthy tissue is essential for maintaining the health and function of the body.

GPC4 is also of interest as a potential drug target. Because GPC4 is highly expressed in various tissues throughout the body, it is a potential target for a variety of therapies. For example, doctors may be interested in using GPC4 as a biomarker to predict the effectiveness of certain treatments. Additionally, GPC4 may also be a useful target for drugs that are designed to inhibit cell proliferation or death.

Overall, GPC4 is a unique and important protein that plays a critical role in the regulation of cell proliferation and tissue formation. Its functions in cell signaling and tissue repair make it an attractive target for a variety of therapies. Further research is needed to fully understand the role of GPC4 in the regulation of cell biology, and to determine its potential as a drug target.

Protein Name: Glypican 4

Functions: Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system (By similarity)

More Common Targets

GPC5 | GPC5-AS1 | GPC5-AS2 | GPC6 | GPC6-AS1 | GPC6-AS2 | GPCPD1 | GPD1 | GPD1L | GPD2 | GPER1 | GPHA2 | GPHB5 | GPHN | GPI | GPI transamidase complex | GPI-GlcNAc transferase complex | GPIHBP1 | GPKOW | GPLD1 | GPM6A | GPM6B | GPN1 | GPN2 | GPN3 | GPNMB | GPR101 | GPR107 | GPR108 | GPR119 | GPR12 | GPR132 | GPR135 | GPR137 | GPR137B | GPR137C | GPR139 | GPR141 | GPR142 | GPR143 | GPR146 | GPR148 | GPR149 | GPR15 | GPR150 | GPR151 | GPR152 | GPR153 | GPR155 | GPR156 | GPR157 | GPR158 | GPR158-AS1 | GPR15LG | GPR160 | GPR161 | GPR162 | GPR17 | GPR171 | GPR173 | GPR174 | GPR176 | GPR179 | GPR18 | GPR180 | GPR182 | GPR183 | GPR19 | GPR199P | GPR20 | GPR21 | GPR22 | GPR25 | GPR26 | GPR27 | GPR3 | GPR31 | GPR32 | GPR33 | GPR34 | GPR35 | GPR37 | GPR37L1 | GPR39 | GPR4 | GPR42 | GPR45 | GPR50 | GPR52 | GPR55 | GPR6 | GPR61 | GPR62 | GPR63 | GPR65 | GPR68 | GPR75 | GPR75-ASB3 | GPR78 | GPR79