Target Name: GPD1
NCBI ID: G2819
Other Name(s): FLJ26652 | GPDH-C | glycerol-3-phosphate dehydrogenase 1 | Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (isoform 1) | glycerol-3-phosphate dehydrogenase 1 (soluble) | GPD-C | HTGTI | glycerophosphate dehydrogenase | Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic | GPD1 variant 1 | Glycerol-3-phosphate dehydrogenase 1 (soluble) | epididymis secretory sperm binding protein | GPDA_HUMAN | glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic | Glycerol-3-phosphate dehydrogenase 1, transcript variant 1 | Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

Understanding GPD1: A Potential Drug Target

GPD1 (G protein-coupled receptor 1) is a protein that is expressed in many different tissues and cells in the body. It is a member of the G protein-coupled receptor family, which is a large superfamily of transmembrane proteins that play a key role in cellular signaling. GPD1 is one of the most well-studied G protein-coupled receptors, and is known for its role in a wide range of physiological processes, including sensory perception, neurotransmitter signaling, and cellular signaling.

GPD1 is an isoform and there are several different genotypes. GPD1 genotypes include wild type (WT), deleted modified gene (DM), and mutant genotypes. The protein encoded by the WT genotype contains 514 amino acids, while the protein encoded by the DM genotype contains only 489 amino acids. The protein encoded by the Mutant genotype contains 522 amino acids, which is 3 more amino acids than the WT genotype.

GPD1 is a membrane protein found on the inside of the cell membrane. It has five transmembrane alpha helices, one on the inside of the cell membrane and the other four on the outside. The 伪-helix of GPD1 consists of 35 amino acids and accounts for 36.5% of the total protein.

GPD1 is a ligand-binding protein that can bind ligand molecules, such as drugs, chemicals, or other signaling molecules. The ligand binding site of GPD1 is located on the outside of the cell membrane. Through ligand binding, GPD1 can trigger a series of signal transduction pathways to regulate cellular physiological processes.

Because GPD1 plays an important role in a variety of physiological processes, it is considered a potential drug target. Researchers are exploring the role of GPD1 in treating a variety of diseases, including neurological diseases, endocrine diseases, and cardiovascular diseases.

As a drug target, GPD1 has high research value. First, by studying the pharmacological properties of GPD1, we can better understand the mechanism of action of drugs and provide guidance for the development of new drugs. Secondly, studying the role of GPD1 in disease can provide new treatment methods and drug targets for medicine. Finally, studying the structure and function of GPD1 can provide new ideas and methods for drug design.

GPD1 is an important drug target with broad application prospects. Further research on the structure and function of GPD1 can provide guidance for the development of new drugs and provide new treatment methods and drug targets for medicine.

Protein Name: Glycerol-3-phosphate Dehydrogenase 1

Functions: Has glycerol-3-phosphate dehydrogenase activity

More Common Targets

GPD1L | GPD2 | GPER1 | GPHA2 | GPHB5 | GPHN | GPI | GPI transamidase complex | GPI-GlcNAc transferase complex | GPIHBP1 | GPKOW | GPLD1 | GPM6A | GPM6B | GPN1 | GPN2 | GPN3 | GPNMB | GPR101 | GPR107 | GPR108 | GPR119 | GPR12 | GPR132 | GPR135 | GPR137 | GPR137B | GPR137C | GPR139 | GPR141 | GPR142 | GPR143 | GPR146 | GPR148 | GPR149 | GPR15 | GPR150 | GPR151 | GPR152 | GPR153 | GPR155 | GPR156 | GPR157 | GPR158 | GPR158-AS1 | GPR15LG | GPR160 | GPR161 | GPR162 | GPR17 | GPR171 | GPR173 | GPR174 | GPR176 | GPR179 | GPR18 | GPR180 | GPR182 | GPR183 | GPR19 | GPR199P | GPR20 | GPR21 | GPR22 | GPR25 | GPR26 | GPR27 | GPR3 | GPR31 | GPR32 | GPR33 | GPR34 | GPR35 | GPR37 | GPR37L1 | GPR39 | GPR4 | GPR42 | GPR45 | GPR50 | GPR52 | GPR55 | GPR6 | GPR61 | GPR62 | GPR63 | GPR65 | GPR68 | GPR75 | GPR75-ASB3 | GPR78 | GPR79 | GPR82 | GPR83 | GPR84 | GPR84-AS1 | GPR85 | GPR87 | GPR88 | GPR89A