Target Name: GPATCH11
NCBI ID: G253635
Other Name(s): centromere protein Y | OTTHUMP00000158585 | G patch domain-containing protein 11 | g patch domain-containing protein 11 | GPATCH11 variant 1 | CCDC75 | G-patch domain containing 11 | GPT11_HUMAN | coiled-coil domain containing 75 | Centromere protein Y | CENP-Y | G patch domain-containing protein 11 isoform 1 | G patch domain containing 11 | coiled-coil domain-containing protein 75 | CENPY | G-patch domain containing 11, transcript variant 1 | FLJ38348

GPATCH11: A Protein Involved in Cancer Development and Treatment

GPATCH11, also known as centromere protein Y, is a protein that is expressed in the centromere region of chromosomes. Its function is not well understood, but it is known to play a role in the regulation of gene expression and to be involved in the development of cancer.

GPATCH11 is a 21-kDa protein that is expressed in the centromere region of chromosomes. It is one of several proteins that are known to be expressed in this region, including the protein CENPAS and the RNA binding protein PRDM1.

The function of GPATCH11 is not well understood, but it is known to play a role in the regulation of gene expression and in the development of cancer.

One of the functions of GPATCH11 is to regulate the activity of chromatin-remodeling complexes, which are responsible for reassembling disrupted chromatin into functional chromatin. This is important for the regulation of gene expression and for the development of cancer.

In addition to its role in regulating chromatin remodeling, GPATCH11 is also thought to be involved in the development of cancer. Several studies have shown that GPATCH11 is highly expressed in various types of cancer, including breast, ovarian, and colorectal cancer. Additionally, experiments have shown that inhibition of GPATCH11 has anti-tumor effects in various cancer cell lines and models.

GPATCH11 is also a potential drug target for cancer treatment. Several studies have shown that inhibition of GPATCH11 has drug-like properties in various cancer cell lines and models. For example, one study published in the journal Nature Communications found that inhibition of GPATCH11 led to a significant reduction in the growth of cancer cells.

Another study published in the journal Oncology Reports found that inhibition of GPATCH11 led to the apoptosis (programmed cell death) of cancer cells. This is important because the apoptosis of cancer cells is a key mechanism of cancer treatment.

In conclusion, GPATCH11 is a protein that is expressed in the centromere region of chromosomes and is involved in the regulation of gene expression and the development of cancer. It is a potential drug target for cancer treatment and its function is an important area of research in the field of cancer biology. Further studies are needed to fully understand the role of GPATCH11 in the development and treatment of cancer.

Protein Name: G-patch Domain Containing 11

More Common Targets

GPATCH2 | GPATCH2L | GPATCH3 | GPATCH4 | GPATCH8 | GPBAR1 | GPBP1 | GPBP1L1 | GPC1 | GPC1-AS1 | GPC2 | GPC3 | GPC4 | GPC5 | GPC5-AS1 | GPC5-AS2 | GPC6 | GPC6-AS1 | GPC6-AS2 | GPCPD1 | GPD1 | GPD1L | GPD2 | GPER1 | GPHA2 | GPHB5 | GPHN | GPI | GPI transamidase complex | GPI-GlcNAc transferase complex | GPIHBP1 | GPKOW | GPLD1 | GPM6A | GPM6B | GPN1 | GPN2 | GPN3 | GPNMB | GPR101 | GPR107 | GPR108 | GPR119 | GPR12 | GPR132 | GPR135 | GPR137 | GPR137B | GPR137C | GPR139 | GPR141 | GPR142 | GPR143 | GPR146 | GPR148 | GPR149 | GPR15 | GPR150 | GPR151 | GPR152 | GPR153 | GPR155 | GPR156 | GPR157 | GPR158 | GPR158-AS1 | GPR15LG | GPR160 | GPR161 | GPR162 | GPR17 | GPR171 | GPR173 | GPR174 | GPR176 | GPR179 | GPR18 | GPR180 | GPR182 | GPR183 | GPR19 | GPR199P | GPR20 | GPR21 | GPR22 | GPR25 | GPR26 | GPR27 | GPR3 | GPR31 | GPR32 | GPR33 | GPR34 | GPR35 | GPR37 | GPR37L1 | GPR39 | GPR4 | GPR42 | GPR45