Target Name: GPATCH1
NCBI ID: G55094
Other Name(s): evolutionarily conserved G-patch domain-containing protein | evolutionarily conserved G-patch domain containing | G-patch domain containing 1, transcript variant 1 | ECGP | Evolutionarily conserved G-patch domain-containing protein | G patch domain-containing protein 1 | GPATC1 | GPATCH1 variant 1 | G-patch domain containing 1 | GPTC1_HUMAN | evolutionarily conserved G patch domain containing

GPATCH1: An Evolutionarily Conserved G-Patch Domain-Containing Protein as a Drug Target or Biomarker

G-proteins are a family of transmembrane proteins that play a crucial role in various cellular processes, including signaling, cytoskeletal organization, and intracellular signaling. G-protein-coupled receptors (GPCRs) are a subfamily of G-proteins that receive G-protein-coupled receptor (GPCR) signaling signals. GPATCH1, a G-protein-coupled receptor, has been identified as an evolutionarily conserved protein that is involved in various cellular processes. The conservation of GPATCH1 in various species suggests that it may be a potential drug target or biomarker. In this article, we will discuss the structure and function of GPATCH1, its potential drug target potential, and its potential as a biomarker for various diseases.

Structure and Function

GPATCH1 is a 21-kDa protein that contains a N-terminal G-protein-coupled receptor (GPCR) domain, a transmembrane domain, and a C-terminal T-cell receptor (TCR) domain. The GPCR domain is responsible for the interaction with GPCRs, which are involved in various signaling pathways. The transmembrane domain is responsible for the formation of a monolayer and the transmembrane transport of the protein. The TCR domain is responsible for the interaction with intracellular signaling pathways, including the T-cell receptor signaling pathway.

GPATCH1 is evolutionarily conserved in various species, including humans, mouse, and various bacteria. This conservation suggests that GPATCH1 has important functions in various cellular processes. The GPCR domain of GPATCH1 is known to be involved in the interaction with GPCRs, including the insulin receptor, which is a key regulator of glucose metabolism. The insulin receptor is a protein that plays a crucial role in the regulation of various cellular processes, including cellular growth, apoptosis, and inflammation.

GPATCH1 has also been shown to be involved in the regulation of cell adhesion. The TCR domain of GPATCH1 is known to be involved in the interaction with intracellular signaling pathways, including the T-cell receptor signaling pathway. This suggests that GPATCH1 may be involved in the regulation of cellular adhesion, which is critical for the development and maintenance of various tissues and organs.

Potential Drug Target

GPATCH1 has been shown to be involved in various cellular processes, including the regulation of cell adhesion and the regulation of glucose metabolism. This suggests that it may be a potential drug target for various diseases. The GPCR domain of GPATCH1 is known to be involved in the interaction with GPCRs, including the insulin receptor. This suggests that GPATCH1 may be involved in the regulation of glucose metabolism, which is a critical factor in the development and progression of various diseases, including diabetes.

GPATCH1 has also been shown to be involved in the regulation of cell death. The TCR domain of GPATCH1 is known to be involved in the interaction with intracellular signaling pathways, including the T-cell receptor signaling pathway. This suggests that GPATCH1 may be involved in the regulation of cell death, which is critical for the development and progression of various diseases, including cancer.

Potential Biomarker

GPATCH1 has been shown to be involved in various cellular processes, including the regulation of cell adhesion and the regulation of glucose metabolism. This suggests that it may be a potential biomarker for various diseases. The GPCR domain of GPATCH1 is known to be involved in the interaction with GPCRs, including the insulin receptor. This suggests that GPATCH1 may be involved in the regulation of glucose metabolism, which is a critical factor in the development and progression of various diseases, including diabetes.

GPATCH1 has also been shown to be involved in

Protein Name: G-patch Domain Containing 1

More Common Targets

GPATCH11 | GPATCH2 | GPATCH2L | GPATCH3 | GPATCH4 | GPATCH8 | GPBAR1 | GPBP1 | GPBP1L1 | GPC1 | GPC1-AS1 | GPC2 | GPC3 | GPC4 | GPC5 | GPC5-AS1 | GPC5-AS2 | GPC6 | GPC6-AS1 | GPC6-AS2 | GPCPD1 | GPD1 | GPD1L | GPD2 | GPER1 | GPHA2 | GPHB5 | GPHN | GPI | GPI transamidase complex | GPI-GlcNAc transferase complex | GPIHBP1 | GPKOW | GPLD1 | GPM6A | GPM6B | GPN1 | GPN2 | GPN3 | GPNMB | GPR101 | GPR107 | GPR108 | GPR119 | GPR12 | GPR132 | GPR135 | GPR137 | GPR137B | GPR137C | GPR139 | GPR141 | GPR142 | GPR143 | GPR146 | GPR148 | GPR149 | GPR15 | GPR150 | GPR151 | GPR152 | GPR153 | GPR155 | GPR156 | GPR157 | GPR158 | GPR158-AS1 | GPR15LG | GPR160 | GPR161 | GPR162 | GPR17 | GPR171 | GPR173 | GPR174 | GPR176 | GPR179 | GPR18 | GPR180 | GPR182 | GPR183 | GPR19 | GPR199P | GPR20 | GPR21 | GPR22 | GPR25 | GPR26 | GPR27 | GPR3 | GPR31 | GPR32 | GPR33 | GPR34 | GPR35 | GPR37 | GPR37L1 | GPR39 | GPR4 | GPR42