Target Name: GPANK1
NCBI ID: G7918
Other Name(s): G-patch domain and ankyrin repeats 1 | G-patch domain and ankyrin repeats 1, transcript variant 1 | Ankyrin repeat domain-containing protein 59 | GPAN1_HUMAN | G patch domain containing 10 | G patch domain and ankyrin repeats-containing protein 1 | OTTHUMP00000070448 | G patch domain-containing protein 10 | OTTHUMP00000029248 | Protein G5 | Protein BAT4 | OTTHUMP00000029244 | GPANK1 variant 1 | GPANK1 variant 2 | HLA-B associated transcript-4 | protein G5 | BAT4 | HLA-B associated transcript 4 | G-patch domain and ankyrin repeats 1, transcript variant 2 | GPATCH10 | G5 | g patch domain-containing protein 10 | HLA-B-associated transcript 4 | G patch domain and ankyrin repeat-containing protein 1 | G patch domain and ankyrin repeats 1 | ANKRD59 | D6S54E | protein BAT4 | ankyrin repeat domain-containing protein 59 | Ankyrin repeat domain 59

GPANK1: A Potential Drug Target Or Biomarker

G-patch domain and ankyrin repeats 1 (GPANK1) are a unique genetic signature that have been identified in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. These repetitive sequences are highly conserved across different species, and their presence suggests that they may play a critical role in the development and progression of these diseases. While more research is needed to fully understand the function of GPANK1, its potential as a drug target or biomarker is an exciting area of study that could have significant implications for the treatment of these diseases.

Current Knowledge of GPANK1

GPANK1 is a highly conserved protein that is found in various cell types, including neurons, immune cells, and tissues. It is composed of a unique nucleotide repeat sequence, which consists of a dinucleotide (dNTPs) of guanine (G) and cytosine (C) followed by a repeat of the sequence G-C-A-G. This repeat sequence is present in multiple genes, including GPANK1, GPK2, and GPK3.

Studies have shown that GPANK1 is involved in various cellular processes, including cell signaling, DNA replication, and stress response. It has also been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Functions of GPANK1

GPANK1 is involved in several cellular processes that are crucial for the proper functioning of cells. One of its functions is to regulate cell signaling pathways, which are the processes by which cells communicate with each other and with the surrounding environment. GPANK1 has been shown to play a role in the regulation of several signaling pathways, including the Wnt signaling pathway, which is involved in the development and maintenance of tissues and organs.

In addition to its role in cell signaling, GPANK1 is also involved in the regulation of DNA replication. This is important for the maintenance of genetic diversity and the development of new organisms. GPANK1 has been shown to play a role in the regulation of DNA replication in various cell types, including cancer cells.

GPANK1 is also involved in the regulation of stress responses. Stress can have a negative impact on the proper functioning of cells, and GPANK1 is involved in the regulation of stress responses to ensure that cells are able to withstand and recover from stress.

Potential Therapeutic Applications

The unique function of GPANK1 makes it an attractive drug target or biomarker for the treatment of various diseases. One potential therapeutic application for GPANK1 is the treatment of cancer. Cancer is a disease that can be highly resistant to traditional therapies, and there is a need for new and effective approaches to treatment. GPANK1 has been shown to play a role in the development and progression of various cancers, including breast, ovarian, and prostate cancers. Therefore, targeting GPANK1 with drugs that can inhibit its function could be a promising approach to the treatment of cancer.

Another potential therapeutic application for GPANK1 is the treatment of neurodegenerative diseases. Neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, are characterized by the progressive loss of brain cells and the development of neurofibrillary tangles. GPANK1 has been shown to play a role in the development and progression of these diseases, and targeting its function with drugs that can inhibit its activity could be a promising approach to the treatment of these diseases.

GPANK1 is also a potential biomarker for the diagnosis and monitoring of autoimmune disorders. Autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis, are characterized by the immune system attacking the body's own tissues. GPANK1 has been shown to play a role in the development and progression of these disorders, and using it as a biomarker to monitor the effectiveness of treatments could be a promising approach to the diagnosis and treatment of autoimmune disorders.

Conclusion

GPANK1 is a unique genetic signature that has been identified in various diseases. Its presence suggests that it may play a critical role in the development and progression of these diseases. While more research is needed to fully understand the function of GPANK1

Protein Name: G-patch Domain And Ankyrin Repeats 1

More Common Targets

GPAT2 | GPAT3 | GPAT4 | GPATCH1 | GPATCH11 | GPATCH2 | GPATCH2L | GPATCH3 | GPATCH4 | GPATCH8 | GPBAR1 | GPBP1 | GPBP1L1 | GPC1 | GPC1-AS1 | GPC2 | GPC3 | GPC4 | GPC5 | GPC5-AS1 | GPC5-AS2 | GPC6 | GPC6-AS1 | GPC6-AS2 | GPCPD1 | GPD1 | GPD1L | GPD2 | GPER1 | GPHA2 | GPHB5 | GPHN | GPI | GPI transamidase complex | GPI-GlcNAc transferase complex | GPIHBP1 | GPKOW | GPLD1 | GPM6A | GPM6B | GPN1 | GPN2 | GPN3 | GPNMB | GPR101 | GPR107 | GPR108 | GPR119 | GPR12 | GPR132 | GPR135 | GPR137 | GPR137B | GPR137C | GPR139 | GPR141 | GPR142 | GPR143 | GPR146 | GPR148 | GPR149 | GPR15 | GPR150 | GPR151 | GPR152 | GPR153 | GPR155 | GPR156 | GPR157 | GPR158 | GPR158-AS1 | GPR15LG | GPR160 | GPR161 | GPR162 | GPR17 | GPR171 | GPR173 | GPR174 | GPR176 | GPR179 | GPR18 | GPR180 | GPR182 | GPR183 | GPR19 | GPR199P | GPR20 | GPR21 | GPR22 | GPR25 | GPR26 | GPR27 | GPR3 | GPR31 | GPR32 | GPR33 | GPR34 | GPR35 | GPR37