Target Name: GON7
NCBI ID: G84520
Other Name(s): C14orf142 | GON7 subunit of KEOPS complex | EKC/KEOPS complex subunit GON7 | GON7, KEOPS complex subunit homolog | Uncharacterized protein C14orf142 | uncharacterized protein C14orf142 | GON7_HUMAN | PNAS-127

GON7 as A Potential Drug Target Or Biomarker for Neurological Disorders

GON7 (C14orf142), a protein that is expressed in various tissues throughout the body, including the brain, has been identified as a potential drug target or biomarker for various neurological and psychiatric disorders. The protein is involved in a variety of cellular processes, including cell signaling, DNA replication, and stress response. Its function has been studied extensively, and several studies have suggested that it may play a role in the development and progression of various neurological disorders.

One of the key functions of GON7 is its role in cell signaling. GON7 is a member of the T-cell signaling pathway, which is involved in the regulation of immune responses and cell signaling. T-cells are a type of immune cell that play a critical role in protecting the body against infection and disease. The T-cell signaling pathway is important for the development and maintenance of T-cell health and function.

GON7 is involved in the regulation of several key events that are critical for T-cell health and function. For example, GON7 has been shown to play a role in the regulation of T-cell proliferation and differentiation. Studies have shown that GON7 can induce T-cell proliferation and promote the development of functional T-cells. GON7 has also been shown to play a role in the regulation of T-cell death, which is important for maintaining T-cell homeostasis and preventing autoimmune diseases.

Another function of GON7 is its role in DNA replication. GON7 is a transcription factor that is involved in the regulation of gene expression. GON7 has been shown to play a role in the regulation of DNA replication, which is critical for the development and maintenance of cellular DNA.

In addition to its role in cell signaling and DNA replication, GON7 is also involved in the regulation of stress response. GON7 is a stress-responsive protein that is involved in the regulation of cellular stress responses. Studies have shown that GON7 can play a role in the regulation of cellular stress responses, which are important for maintaining cellular homeostasis and preventing stress-induced diseases.

GON7 has also been identified as a potential drug target or biomarker for several neurological and psychiatric disorders. For example, GON7 has been shown to be involved in the development and progression of multiple sclerosis, a progressive neurodegenerative disorder that affects the central nervous system. Studies have shown that GON7 is involved in the regulation of cellular processes that are important for the development and progression of MS, and that inhibition of GON7 activity may be a potential therapeutic approach for treating MS.

GON7 has also been shown to be involved in the development and progression of other neurological disorders, including Alzheimer's disease and Parkinson's disease. Studies have shown that GON7 is involved in the regulation of cellular processes that are important for the development and progression of these disorders, and that inhibition of GON7 activity may be a potential therapeutic approach for treating these disorders.

In addition to its potential therapeutic applications, GON7 has also been identified as a potential biomarker for several neurological and psychiatric disorders. For example, GON7 has been shown to be involved in the regulation of cellular processes that are important for the development and progression of MS, and may be a potential biomarker for this disorder. GON7 has also been shown to be involved in the regulation of cellular processes that are important for the development and progression of other neurological disorders, including Alzheimer's disease and Parkinson's disease. These findings suggest that GON7 may be a useful biomarker or drug target for these disorders.

In conclusion, GON7 is a protein that is involved in a variety of cellular processes that are important for maintaining cellular homeostasis and regulating cellular signaling, DNA replication, and stress responses. Its function has been studied extensively, and several studies have suggested that it may play a role in the development and progression of various neurological and psychiatric disorders. As a potential drug target or biomarker, GON7 may be a useful therapeutic approach for treating these disorders. Further research is needed to fully understand the role of GON7 in

Protein Name: GON7 Subunit Of KEOPS Complex

Functions: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (PubMed:27903914, PubMed:31481669). The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 (PubMed:27903914, PubMed:31481669). GON7 plays a supporting role to the catalytic subunit OSGEP in the complex (PubMed:27903914, PubMed:31481669)

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